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[A program for analysis of dose-response relationship with logistic model].

作者信息

Wang N, Zhao D H, Sheng B H

机构信息

Department of Pharmacology, Fourth Military Medical College, Xi-an, China.

出版信息

Zhongguo Yao Li Xue Bao. 1990 Mar;11(2):187-92.

PMID:2275397
Abstract

In order to avoid the defects in common methods for analysis of dose-response curves, we fit groups of dose-response curves simultaneously or separately on computer by using logistic model, with the EC50 and slope factor as the basic parameters. The pD2 and pA2 values were calculated from the best estimated EC50s. This method shows a good compatibility with the original experimental data. The BASIC program can be conveniently run on microcomputers.

摘要

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