Li Yiping, Payner Troy D, Cohen-Gadol Aaron A
Goodman Campbell Brain and Spine, Indiana University Department of Neurological Surgery Indianapolis, Indiana, USA.
Surg Neurol Int. 2012;3:66. doi: 10.4103/2152-7806.97168. Epub 2012 Jun 19.
Recent studies have hypothesized that hemodynamic changes in parent vessels are responsible for the formation and regression of cerebral aneurysms. One author has described regression of a "flow-related" 4-mm posterior communicating artery (PCoA) aneurysm following ipsilateral carotid endarterectomy (CEA), resulting in reversal of blood flow in the PCoA.
We report a 68-year-old woman with a coincidental intracranial aneurysm (ICA) and contralateral internal carotid artery stenosis. The aneurysm spontaneously regressed subsequent to contralateral ICA endarterectomy as documented by repeat computed tomographic angiography. This report also demonstrates the first known case of an ICA in the anterior cerebral artery territory to undergo spontaneous regression.
We conclude that the regression and potentially the formation of this aneurysm correlated with hemodynamic factors associated with stenosis of the contralateral ICA.
最近的研究推测,母血管中的血流动力学变化是脑动脉瘤形成和消退的原因。一位作者描述了一例“血流相关”的4毫米后交通动脉(PCoA)动脉瘤在同侧颈动脉内膜切除术(CEA)后消退,导致PCoA血流逆转。
我们报告一名68岁女性,患有巧合的颅内动脉瘤(ICA)和对侧颈内动脉狭窄。经重复计算机断层血管造影证实,对侧ICA内膜切除术后动脉瘤自发消退。本报告还展示了大脑前动脉区域首例已知自发消退的ICA病例。
我们得出结论,该动脉瘤的消退以及可能的形成与对侧ICA狭窄相关的血流动力学因素有关。