如何构建 DNA 解旋酶。
How to build a DNA unwinding machine.
机构信息
DNA:Protein Interactions Unit, School of Biochemistry, Medical Sciences Building, University of Bristol, BS8 1TD, UK.
出版信息
Structure. 2012 Jul 3;20(7):1127-8. doi: 10.1016/j.str.2012.06.006.
PMID:22770366
Abstract
In this issue of Structure, He and colleagues present the crystal structure of the phage T4 Dda helicase bound to DNA, providing new insights into how this protein efficiently couples single-stranded DNA translocation to DNA strand separation.
摘要
本期《结构》中，何川及其同事呈现了噬菌体 T4 Dda 解旋酶与 DNA 复合物的晶体结构，为深入了解该蛋白如何高效将单链 DNA 易位与 DNA 链分离相偶联提供了新的见解。
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