ACS 化学神经科学分子特写：Saphris。
ACS chemical neuroscience molecule spotlight on Saphris.
机构信息
Vanderbilt University, Vanderbilt University Medical Center Department of Pharmacology, and Vanderbilt Program in Drug Discovery, Nashville, Tennessee, USA.
出版信息
ACS Chem Neurosci. 2010 Apr 21;1(4):263-4. doi: 10.1021/cn100022a.
Abstract
On August 14th, 2009, for the first time, the FDA has approved a psychotropic medication for two indications simultaneously. Saphris (asenapine) is a multitarget atypical antipsychotic medication approved to treat adults with schizophrenia and bipolar I disorder.
摘要
2009 年 8 月 14 日，FDA 首次同时批准一种精神药物用于两种适应证。Saphris（阿塞那平）是一种多靶标非典型抗精神病药物，获批用于治疗精神分裂症成年患者和双相 I 型障碍患者。
相似文献
1
ACS chemical neuroscience molecule spotlight on Saphris.
ACS Chem Neurosci. 2010 Apr 21;1(4):263-4. doi: 10.1021/cn100022a.
2
Asenapine.
Nat Rev Drug Discov. 2009 Nov;8(11):843-4. doi: 10.1038/nrd3027.
3
Asenapine (Saphris) sublingual tablets for schizophrenia and bipolar disorder.
Med Lett Drugs Ther. 2010 Feb 8;52(1331):9-10.
4
Asenapine for schizophrenia and bipolar disorder: a review of the efficacy and safety profile for this newly approved sublingually absorbed second-generation antipsychotic.
Int J Clin Pract. 2009 Dec;63(12):1762-84. doi: 10.1111/j.1742-1241.2009.02228.x. Epub 2009 Oct 14.
5
Asenapine: a review of acute and extension phase data in bipolar disorder.
CNS Neurosci Ther. 2011 Dec;17(6):645-8. doi: 10.1111/j.1755-5949.2010.00200.x. Epub 2010 Oct 15.
6
New drug information. Saphris.
JAAPA. 2010 Mar;23(3):16.
7
Iloperidone, asenapine and lurasidone: a primer on their current status.
Expert Opin Pharmacother. 2012 Sep;13(13):1911-22. doi: 10.1517/14656566.2012.712114. Epub 2012 Jul 31.
8
Asenapine maleate: a new drug for the treatment of schizophrenia and bipolar mania.
Drugs Today (Barc). 2009 Dec;45(12):865-76. doi: 10.1358/dot.2009.45.12.1421561.
9
Asenapine: Pharmacological Aspects and Role in Psychiatric Disorders.
Psychiatr Danub. 2019 Jun;31(2):157-161. doi: 10.24869/psyd.2019.157.
10
Paradoxical pinpoint pupils with asenapine.
Asia Pac Psychiatry. 2015 Jun;7(2):230. doi: 10.1111/appy.12171.
本文引用的文献
1
Asenapine: a novel psychopharmacologic agent with a unique human receptor signature.
J Psychopharmacol. 2009 Jan;23(1):65-73. doi: 10.1177/0269881107082944. Epub 2008 Feb 28.
2
Stressful life events preceding the acute onset of schizophrenia: a cross-national study from the World Health Organization.
Cult Med Psychiatry. 1987 Jun;11(2):123-205. doi: 10.1007/BF00122563.
Zotero 插件