[内蒙古牧区蒙古族和汉族老年人群轻度认知功能障碍患病率研究]

[A prevalence study on mild cognitive impairment among the elderly populations of Mongolian and Han nationalities in a pastoral area of Inner Mongolia].

作者信息

Hu Riletemuer, Zhao Shi-gang, Wang De-sheng, Wen Shi-rong, Niu Guang-ming, A Rong, Wang Zhi-guang, Jiang Ming-fang, Zhang Chun-yu

机构信息

Department of Neurology, the First Affiliated Hospital of Inner Mongolia Medical College, Hohhot 010050, China.

出版信息

Zhonghua Liu Xing Bing Xue Za Zhi. 2012 Apr;33(4):364-7.

PMID:22781406

Abstract

OBJECTIVE

To understand the epidemiological characteristics and distribution of mild cognitive impairment (MCI) in elderly populations from Mongolian and Han nationalities living in the pastoral areas of Inner Mongolia Autonomous Region of China.

METHODS

According to the MCI clinical diagnostic criteria from Diagnostic and Statistical Manual of Mental Disorders 4th revised edition (DSM-IV) by American Psychiatric Association, the individuals under study were at the age of 55 or over, with Mongolian or Han ethnicities and living in the pastoral area of Inner Mongolia.

RESULTS

The crude MCI morbidity rates of Mongolian and Han of the study populations in the pastoral area of Inner Mongolia Autonomous Region of China was 19.48% (1782/9146) and the standardization morbidity was 18.98%. The crude MCI morbidity rates of both Mongolian and Han ethnicities were 17.46% (the standardization morbidity was 16.99%) and 20.60% (the standardization morbidity was 19.98%), respectively. There showed a significant positive correlation between the crude morbidities and age, also significantly increasing with the latter. In the Mongolian population, the morbidity increased from 12.17% at the age 55-59 to 27.78% at 85 while in the Han population, the morbidity increased from 15.50% at the age 55-59 to 23.53% at 85. In both the populations of Mongolian and Han, there was a statistically difference found between the morbidities of MCI (χ2=13.229, P=0.000). The morbidity was higher in Hans than in the Mongolians. However, there was no statistically significant difference noticed between the morbidities of MCI in the Mongolian males and females (χ2=2.376, P=0.123). There was statistically significant difference found between the morbidities of MCI in the Han males and females, with females having higher risk than males (χ2=24.470, P=0.000).

CONCLUSION

The morbidity of MCI in the elderly Mongolian and Han populations from the pastoral area of Inner Mongolia Autonomous Region of China was considered to be quite high and correlated to age and gender.

摘要

目的

了解中国内蒙古自治区牧区蒙古族和汉族老年人群轻度认知障碍（MCI）的流行病学特征及分布情况。

方法

根据美国精神医学协会《精神疾病诊断与统计手册》第4版修订版（DSM-IV）的MCI临床诊断标准，研究对象为年龄在55岁及以上、蒙古族或汉族且居住在内蒙古牧区的人群。

结果

中国内蒙古自治区牧区研究人群中蒙古族和汉族的MCI粗发病率为19.48%（1782/9146），标准化发病率为18.98%。蒙古族和汉族的MCI粗发病率分别为17.46%（标准化发病率为16.99%）和20.60%（标准化发病率为19.98%）。粗发病率与年龄呈显著正相关，且随年龄增长显著升高。在蒙古族人群中，发病率从55 - 59岁时的12.17%增至85岁时的27.78%；在汉族人群中，发病率从55 - 59岁时的15.50%增至85岁时的23.53%。蒙古族和汉族人群中，MCI发病率存在统计学差异（χ2 = 13.229，P = 0.000），汉族发病率高于蒙古族。然而，蒙古族男性和女性的MCI发病率无统计学显著差异（χ2 = 2.376，P = 0.123）。汉族男性和女性的MCI发病率存在统计学显著差异，女性患病风险高于男性（χ2 = 24.470，P = 0.000）。