Division of Vascular Surgery, Vita - Salute University, Scientific Institute H. San Raffaele, Milan, Italy.
J Endovasc Ther. 2012 Jun;19(3):370-2. doi: 10.1583/12-3821R.1.
To report endovascular treatment of a ruptured mycotic aneurysm in a patient with previous cardiac surgery, a cardioverter-defibrillator, and an intrathoracic left ventricular assist device (LVAD).
A 75-year-old man was admitted for a syncopal episode and severe back pain. The patient had a past history of postischemic dilatative cardiomyopathy for which a cardioverter-defibrillator was implanted. An LVAD and bioprosthetic aortic valve were subsequently placed due to severe cardiogenic shock. The postoperative course was complicated by methicillin-resistant Staphylococcus aureus mediastinitis and acute renal failure requiring temporary dialysis. At the current admission 4 months later, urgent computed tomography (CT) showed a ruptured aneurysm in the middle third of the descending thoracic aorta; blood cultures were positive for Candida sp . The patient was hemodynamically stable, so he was placed in intensive care and given targeted antimicrobial therapy while an endovascular treatment was planned. At surgery, a rifampicin-soaked Relay Plus 30-mm×95-cm stent-graft was deployed through a right common femoral cutdown to seal the aortic rupture. Successful aneurysm exclusion was confirmed by intraoperative transesophageal echocardiography (TEE). At the 6-month follow-up, the patient was without recurrent pathology or graft infection as demonstrated by CT.
Thoracic endovascular aortic repair in patients with LVAD is peculiar for several aspects: accurate planning is necessary to adequately visualize the aortic lesion despite the presence of many radiopaque devices and the femoral arteries are pulseless. Moreover, extremely slow washout of contrast from the aortic rupture prevents correct assessment of final sac exclusion with angiography; intraoperative TEE monitoring proved extremely useful.
报告 1 例既往有心脏手术、心脏除颤器和胸内左心室辅助装置(LVAD)病史的患者发生感染性真菌性动脉瘤破裂的血管内治疗。
1 例 75 岁男性因晕厥和严重背痛入院。该患者既往有缺血性扩张型心肌病病史,因该疾病植入了心脏除颤器。随后因严重心源性休克放置了 LVAD 和生物瓣主动脉瓣。术后出现耐甲氧西林金黄色葡萄球菌性纵隔炎和急性肾衰竭,需要临时透析,病程复杂。4 个月后,患者目前再次入院,紧急 CT 显示降胸主动脉中段破裂性动脉瘤;血培养阳性为念珠菌属。患者血流动力学稳定,因此被置于重症监护病房,给予靶向抗生素治疗,同时计划进行血管内治疗。手术中,通过右股总动脉切开术放置了浸有利福平的 Relay Plus 30mm×95cm 支架移植物,以密封主动脉破裂口。术中经食管超声心动图(TEE)证实成功排除了动脉瘤。6 个月随访时,CT 显示患者无复发病变或移植物感染。
LVAD 患者的胸主动脉血管内修复具有几个特点:尽管存在许多不透射线装置,但需要准确的规划才能充分显示主动脉病变,并且股动脉无脉搏。此外,主动脉破裂处造影剂的洗脱非常缓慢,防止了正确评估最终囊袋的排除;术中 TEE 监测非常有用。