嗜酸性胃肠道疾病：综述与更新
Eosinophilic gastrointestinal diseases: review and update.
作者信息
Jawairia Mahreema, Shahzad Ghulamullah, Mustacchia Paul
机构信息
Department of Medicine, Nassau University Medical Center, 2201 Hempstead Turnpike, East Meadow, NY 11554, USA.
出版信息
ISRN Gastroenterol. 2012;2012:463689. doi: 10.5402/2012/463689. Epub 2012 Jun 25.
Abstract
Eosinophilic gastrointestinal disorders (EGIDs) are a progressively more frequent diverse group of intestinal diseases. The intention of this paper is to present the newest developments in the care of patients with EGIDs and to sum up a rising literature defining the clinical features and mechanistic elements of eosinophils and their intricate associations with the gastrointestinal tract. Clinicians ought to stay sensitive to EGIDs as a diagnostic likelihood for patients with general gastrointestinal symptoms. Further research is warranted to establish various methods leading to dysfunction coupled with eosinophilic gastrointestinal inflammation.
摘要
嗜酸性粒细胞性胃肠道疾病（EGIDs）是一类日益常见的、多样的肠道疾病。本文旨在介绍EGIDs患者护理方面的最新进展，并总结越来越多的文献，这些文献明确了嗜酸性粒细胞的临床特征和机制要素，以及它们与胃肠道的复杂关联。临床医生应对EGIDs保持警惕，将其作为具有一般胃肠道症状患者的一种诊断可能性。有必要进行进一步研究，以确定导致功能障碍以及嗜酸性粒细胞性胃肠道炎症的各种机制。
相似文献
1
Eosinophilic gastrointestinal diseases: review and update.
ISRN Gastroenterol. 2012;2012:463689. doi: 10.5402/2012/463689. Epub 2012 Jun 25.
2
Update on clinical and immunological features of eosinophilic gastrointestinal diseases.
Curr Opin Gastroenterol. 2011 Oct;27(6):515-22. doi: 10.1097/MOG.0b013e32834b314c.
3
Eosinophilic Gastrointestinal Diseases in Children: A Practical Review.
Curr Pediatr Rev. 2020;16(2):106-114. doi: 10.2174/1573396315666191022154432.
4
Eosinophils, Eosinophilic Gastrointestinal Diseases, and Inflammatory Bowel Disease: A Critical Review.
J Clin Med. 2024 Jul 14;13(14):4119. doi: 10.3390/jcm13144119.
5
The pathology and causes of tissue eosinophilia in the gastrointestinal tract.
Histopathology. 2017 Aug;71(2):177-199. doi: 10.1111/his.13228. Epub 2017 May 26.
6
Eosinophilic Gastrointestinal Diseases in Childhood.
Ann Nutr Metab. 2018;73 Suppl 4:18-28. doi: 10.1159/000493668. Epub 2019 Feb 19.
7
The role of the high-affinity IgE receptor, FcepsilonRI, in eosinophilic gastrointestinal diseases.
Immunol Allergy Clin North Am. 2009 Feb;29(1):159-70, xii. doi: 10.1016/j.iac.2008.09.004.
8
Histopathology associated with eosinophilic gastrointestinal diseases.
Immunol Allergy Clin North Am. 2009 Feb;29(1):109-17, x-xi. doi: 10.1016/j.iac.2008.10.005.
9
Eosinophilic gastrointestinal diseases beyond eosinophilic esophagitis.
Ann Allergy Asthma Immunol. 2018 Aug;121(2):162-167. doi: 10.1016/j.anai.2018.06.013. Epub 2018 Jun 22.
10
Epithelial function in eosinophilic gastrointestinal diseases.
Immunol Allergy Clin North Am. 2009 Feb;29(1):171-8, xii-xiii. doi: 10.1016/j.iac.2008.09.003.
引用本文的文献
1
A Nationwide Retrospective Analysis of Socioeconomic Factors Associated With Eosinophilic Colitis: A Population-Based Study.
Gastro Hep Adv. 2025 Mar 22;4(7):100663. doi: 10.1016/j.gastha.2025.100663. eCollection 2025.
2
Small Bowel Imaging from Stepchild of Roentgenology to MR Enterography, Part II: The Reliable Disclosure of Crohn's Disease and Non-Inflammatory Small Bowel Disorder Plot through MRI Findings.
Life (Basel). 2023 Aug 30;13(9):1836. doi: 10.3390/life13091836.
3
Quantity and Distribution of Eosinophils in the Adult Human Gastric Specimens.
Iran J Pathol. 2022 Spring;17(2):166-173. doi: 10.30699/IJP.2022.537842.2706. Epub 2022 Feb 20.
4
Eosinophilic Ascites: A Rare Case Report With Diagnostic and Therapeutic Challenges.
Cureus. 2020 Nov 6;12(11):e11362. doi: 10.7759/cureus.11362.
5
Heart disease in a mutant mouse model of spontaneous eosinophilic myocarditis maps to three loci.
BMC Genomics. 2019 Oct 11;20(1):727. doi: 10.1186/s12864-019-6108-0.
6
A rare case of eosinophilic esophagitis and eosinophilic subserosal gastroenteritis with ascites.
Turk J Gastroenterol. 2019 Sep;30(9):851-853. doi: 10.5152/tjg.2019.18680.
7
Gastrointestinal Manifestations of Hypereosinophilic Syndromes and Mast Cell Disorders: a Comprehensive Review.
Clin Rev Allergy Immunol. 2019 Oct;57(2):194-212. doi: 10.1007/s12016-018-8695-y.
8
Oxaliplatin-induced changes in microbiota, TLR4+ cells and enhanced HMGB1 expression in the murine colon.
PLoS One. 2018 Jun 12;13(6):e0198359. doi: 10.1371/journal.pone.0198359. eCollection 2018.
9
Classification of eosinophilic disorders of the small and large intestine.
Virchows Arch. 2018 Jan;472(1):15-28. doi: 10.1007/s00428-017-2249-1. Epub 2017 Nov 10.
10
Eosinophilic Gastroenteritis: An Underdiagnosed Condition.
Dig Dis Sci. 2016 Sep;61(9):2585-92. doi: 10.1007/s10620-016-4203-5. Epub 2016 May 27.
本文引用的文献
1
Histopathologic diagnosis of eosinophilic conditions in the gastrointestinal tract.
Adv Anat Pathol. 2011 Sep;18(5):335-48. doi: 10.1097/PAP.0b013e318229bfe2.
2
Understanding eosinophilic esophagitis: the cellular and molecular mechanisms of an emerging disease.
Mucosal Immunol. 2011 Mar;4(2):139-47. doi: 10.1038/mi.2010.88. Epub 2011 Jan 12.
3
Eosinophilic gastritis: histopathological characterization and quantification of the normal gastric eosinophil content.
Mod Pathol. 2011 Apr;24(4):556-63. doi: 10.1038/modpathol.2010.221. Epub 2010 Dec 17.
4
Primary eosinophilic disorders of the gastrointestinal tract.
Gut. 2009 May;58(5):721-32. doi: 10.1136/gut.2008.165894. Epub 2008 Dec 3.
5
Anti-IL-5 (mepolizumab) therapy reduces eosinophil activation ex vivo and increases IL-5 and IL-5 receptor levels.
J Allergy Clin Immunol. 2008 Jun;121(6):1473-83, 1483.e1-4. doi: 10.1016/j.jaci.2008.02.033. Epub 2008 Apr 14.
6
Comparison of oral prednisone and topical fluticasone in the treatment of eosinophilic esophagitis: a randomized trial in children.
Clin Gastroenterol Hepatol. 2008 Feb;6(2):165-73. doi: 10.1016/j.cgh.2007.11.008.
7
Update on hidden food allergens and food labeling.
Allergy Asthma Proc. 2007 Nov-Dec;28(6):634-9. doi: 10.2500/aap.2007.6.3066.
8
Anti-IgE treatment of eosinophil-associated gastrointestinal disorders.
J Allergy Clin Immunol. 2007 Sep;120(3):594-601. doi: 10.1016/j.jaci.2007.06.015.
9
Eosinophil trafficking in allergy and asthma.
J Allergy Clin Immunol. 2007 Jun;119(6):1303-10; quiz 1311-2. doi: 10.1016/j.jaci.2007.03.048. Epub 2007 May 3.
10
Is there a seasonal variation in the incidence or intensity of allergic eosinophilic esophagitis in newly diagnosed children?
J Clin Gastroenterol. 2007 May-Jun;41(5):451-3. doi: 10.1097/01.mcg.0000248019.16139.67.
Zotero 插件