Whittemore Kenneth R, Dornan Briana K, Lally Tara, Dargie Jenna M
Department of Otolaryngology and Communication Enhancement, Boston Children's Hospital, Boston, MA 02115, United States.
Int J Pediatr Otorhinolaryngol. 2012 Oct;76(10):1465-70. doi: 10.1016/j.ijporl.2012.06.022. Epub 2012 Jul 12.
Described is a case series of clinical findings in children with persistent conductive or mixed hearing loss following tympanostomy tube placement for serous otitis media.
Retrospective chart review.
Tertiary pediatric hospital.
SUBJECTS/METHODS: Medical records of thirty-nine children who were referred for either conductive or mixed hearing loss post-tympanostomy tube placement were reviewed for clinical histories, physical examinations, audiological evaluations, diagnostic studies, consultations, and surgical findings. Approval was obtained from the Boston Children's Hospital Institutional Review Board.
Causes of hearing loss included ossicular abnormalities, cochlear abnormalities, 'third window' effects, cholesteatomas, genetic syndromes, and unknown causes. In four patients with isolated mild low-frequency conductive hearing loss, the cause was the presence of functional tubes. All patients diagnosed with a genetic syndrome had bilateral hearing loss. Patients with mixed hearing loss were diagnosed with cochlear abnormalities, 'third window' effects, or genetic syndromes. Computed tomography led to diagnosis in sixteen of twenty-five patients. Vestibular-evoked myogenic potential testing suggested a diagnosis in three of four patients.
In children with persistent hearing loss following tympanostomy tube placement, identifying the laterality and type of hearing loss appears to be of importance in diagnosis. Patients with bilateral hearing loss should be considered for genetic testing, given the possibility of a syndrome. Patients identified with a mixed hearing loss should be evaluated for inner ear anomalies. Patients with mild, low-frequency hearing losses should be monitored audiologically and investigated further only if the hearing loss progresses and/or there is no resolution following tube extrusion.
描述一系列因浆液性中耳炎行鼓膜置管术后出现持续性传导性或混合性听力损失的儿童的临床发现。
回顾性病历审查。
三级儿科医院。
研究对象/方法:对39例因鼓膜置管术后出现传导性或混合性听力损失而转诊的儿童的病历进行回顾,内容包括临床病史、体格检查、听力评估、诊断性检查、会诊及手术发现。本研究获得了波士顿儿童医院机构审查委员会的批准。
听力损失的原因包括听骨链异常、耳蜗异常、“第三窗”效应、胆脂瘤、遗传综合征及不明原因。4例单纯轻度低频传导性听力损失患者的病因是功能性置管的存在。所有诊断为遗传综合征的患者均为双侧听力损失。混合性听力损失患者被诊断为耳蜗异常、“第三窗”效应或遗传综合征。25例患者中有16例通过计算机断层扫描得以确诊。4例患者中有3例通过前庭诱发肌源性电位测试得出诊断。
对于鼓膜置管术后仍存在听力损失的儿童,确定听力损失的侧别和类型在诊断中似乎很重要。鉴于存在综合征的可能性,双侧听力损失的患者应考虑进行基因检测。确诊为混合性听力损失的患者应评估内耳异常情况。轻度低频听力损失的患者应进行听力监测,只有在听力损失进展和/或置管脱出后听力未恢复时才需进一步检查。