Division of Chemistry and Biological Chemistry, School of Physical & Mathematical Sciences, Nanyang Technological University, Singapore 637371, Singapore.
Org Biomol Chem. 2012 Aug 28;10(32):6600-6. doi: 10.1039/c2ob25854d. Epub 2012 Jul 13.
A palladacycle-catalyzed tandem Heck-intramolecular aza-Michael reaction protocol has been developed for the one-pot synthesis of 1-substituted isoindolines from N-unprotected 2-bromobenzylamines and acrylates with high yields.
钯环催化的串联 Heck-分子内氮杂迈克尔反应协议已被开发用于从 N-未保护的 2-溴苯甲胺和丙烯酸酯一锅合成 1-取代的异吲哚啉，产率很高。
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