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主动脉疾病组织病理学诊断标准:SIAPEC - IAP“心血管病理学”研究组与意大利心血管病理学会合作达成的共识声明

Criteria for histopathologic diagnosis of aortic disease consensus statement from the SIAPEC-IAP study group of "cardiovascular pathology" in collaboration with the association for Italian cardiovascular pathology.

作者信息

Leone O, Agozzino L, Angelini A, Bartoloni G, Basso C, Caruso G, D'Amati G, Pucci A, Thiene G, Gallo P

机构信息

Department of Pathology, Azienda Ospedaliero-Universitaria S'Orsola-Malpighi, Bologna, Italy.

出版信息

Pathologica. 2012 Feb;104(1):1-33.

Abstract

Nowadays, the histopathological study of surgical specimens is an essential part of the diagnostic work-up in aortic disease, and not only in characterizing the neoplastic forms. Despite increasing clinico-therapeutic complexity of aortic pathology, the criteria for histopathological diagnosis have not been properly updated over the years, with the result that we find inconsistent terminology and little standardization of diagnostic criteria. In light of this consideration, the SIAPeC-IAP Study Group of "Cardiovascular Pathology", in collaboration with the Association for Italian Cardiovascular Pathology, has created this consensus document, with the aim of defining the features of histopathological substrates in the main non-neoplastic aortopathies (atherosclerotic, "degenerative"/non inflammatory, and inflammatory) and of systematizing diagnostic criteria even for the rare tumours of the aorta and pulmonary artery. The principal aims of the project are defining histopathological diagnostic criteria, standard nomenclature and classification, methodology and reporting of histopathological study and handling of aortic specimens. In addiction, some current issues and new knowledge emerging from basic aortic research are debated, with the aim of promoting a "modern" and up-to-date view of aortic pathology.

摘要

如今,手术标本的组织病理学研究是主动脉疾病诊断检查的重要组成部分,而且不仅仅用于表征肿瘤形态。尽管主动脉病理学的临床治疗复杂性日益增加,但多年来组织病理学诊断标准并未得到适当更新,结果我们发现术语不一致,诊断标准也几乎没有标准化。鉴于此,“心血管病理学”SIAPeC-IAP研究小组与意大利心血管病理学会合作,制定了本共识文件,旨在确定主要非肿瘤性主动脉病变(动脉粥样硬化、“退行性”/非炎症性和炎症性)的组织病理学基质特征,并使主动脉和肺动脉罕见肿瘤的诊断标准系统化。该项目的主要目标是确定组织病理学诊断标准、标准命名和分类、组织病理学研究方法及报告以及主动脉标本的处理。此外,还对主动脉基础研究中出现的一些当前问题和新知识进行了讨论,目的是促进对主动脉病理学的“现代”和最新认识。

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