人类妊娠期间对心理压力的生理反应：现有知识和未来方向。
Physiological reactivity to psychological stress in human pregnancy: current knowledge and future directions.
机构信息
Department of Psychiatry, The Ohio State University Medical Center, Columbus, OH 43210, USA.
出版信息
Prog Neurobiol. 2012 Nov;99(2):106-16. doi: 10.1016/j.pneurobio.2012.07.003. Epub 2012 Jul 16.
Abstract
Cardiovascular and neuroendocrine reactivity to acute stress are important predictors of health outcomes in non-pregnant populations. Greater magnitude and duration of physiological responses have been associated with increased risk of hypertensive disorders and diabetes, greater susceptibility to infectious illnesses, suppression of cell-mediated immunity as well as risk for depression and anxiety disorders. Stress reactivity during pregnancy has unique implications for maternal health, birth outcomes, and fetal development. However, as compared to the larger literature, our understanding of the predictors and consequences of exaggerated stress reactivity in pregnancy is limited. This paper reviews the current state of this literature with an emphasis on gaps in knowledge and future directions.
摘要
心血管和神经内分泌对急性应激的反应是预测非妊娠人群健康结果的重要指标。生理反应的幅度和持续时间越大，与高血压疾病和糖尿病的风险增加、对传染病的易感性增加、细胞介导免疫的抑制以及抑郁和焦虑障碍的风险增加有关。怀孕期间的应激反应对母亲的健康、出生结局和胎儿发育有独特的影响。然而，与更大的文献相比，我们对妊娠期间应激反应过度的预测因子和后果的理解是有限的。本文综述了这一文献的现状，重点讨论了知识空白和未来方向。
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