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[颅内巨大动脉瘤的腔内血栓形成及生长机制]

[Intraluminal thrombosis and growth-mechanism of giant intracranial aneurysms].

作者信息

Nagata I, Kikuchi H, Yamagata S, Miyamoto S, Kaneko T, Asato R

机构信息

Department of Neurosurgery, Kyoto University Medical School.

出版信息

No Shinkei Geka. 1990 Dec;18(12):1115-20.

PMID:2280813
Abstract

12 giant intracranial aneurysms were studied by MRI. Intraluminal thrombosis was observed in 9 aneurysms. Thrombosis was found more frequently in larger aneurysms. Thrombi were formed posteriorly or inferiorly in the lumen of 4 among 5 IC-cavernous aneurysms. Location of the neck of the aneurysms and stagnation of blood flow influenced by gravity may be causative factors determining the location of thrombi. In 6 aneurysms intraluminal thrombi were inhomogeneous on MRI, suggesting that the thrombi had been formed at different times. New thrombi were formed between the aneurysmal wall and the old thrombus in 3 cases. Dissection of the aneurysmal wall by residual blood flow in the lumen or hemorrhage in the aneurysmal wall may be one of the growth mechanisms of giant intracranial aneurysms.

摘要

通过磁共振成像(MRI)对12个巨大颅内动脉瘤进行了研究。在9个动脉瘤中观察到腔内血栓形成。血栓在较大的动脉瘤中更常见。在5个颈内动脉海绵窦段动脉瘤中的4个,血栓形成于管腔的后部或下部。动脉瘤颈部的位置以及受重力影响的血流停滞可能是决定血栓位置的致病因素。在6个动脉瘤中,腔内血栓在MRI上不均匀,提示血栓是在不同时间形成的。3例在动脉瘤壁与陈旧血栓之间形成了新血栓。管腔内残余血流对动脉瘤壁的剥离或动脉瘤壁内出血可能是巨大颅内动脉瘤的生长机制之一。

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