环保型取代吡喃并[2,3-c]吡唑的合成与生物评价。
Eco-friendly synthesis and biological evaluation of substituted pyrano[2,3-c]pyrazoles.
机构信息
Crop Protection Chemicals Division, Indian Institute of Chemical Technology, Tarnaka, Hyderabad 500607, India.
出版信息
Bioorg Med Chem Lett. 2012 Aug 15;22(16):5272-8. doi: 10.1016/j.bmcl.2012.06.055. Epub 2012 Jun 29.
PMID:22818081
Abstract
An ecofriendly green approach for synthesis of substituted pyrano[2,3-c]pyrazoles has been developed via a multicomponent one pot approach in aqueous ethanol medium under totally non-catalytic conditions. The synthesized compounds were evaluated for their antibacterial, anti-inflammatory and cytotoxic activities.
摘要
一种环保的绿色方法已经被开发出来，用于通过多组分一锅法在水乙醇介质中，在完全无催化条件下合成取代的吡喃并[2,3-c]吡唑。所合成的化合物被评估了其抗菌、抗炎和细胞毒性活性。
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