Department of Animal Histology and Embryology, Silesian University, 9 Bankowa Str., 40-007 Katowice, Poland.
Micron. 2013 Jan;44:228-37. doi: 10.1016/j.micron.2012.06.013. Epub 2012 Jul 7.
The process of ciliogenesis that accompanies the differentiation of the thyroid gland in grass snake Natrix natrix L. embryos was studied ultrastructurally. Based on this study, it can be concluded that the ciliogenesis occurred in two waves and that new centrioles duplicated via centriolar pathways. The first wave of ciliogenesis started in the post-mitotic thyrocytes before their polarisation. It ended approximately halfway through the developmental period. The second wave of ciliogenesis took place after the polarization of thyrocytes and before the resting phase of the embryonic thyroid. This wave of ciliogenesis stopped shortly before hatching when fully differentiated thyrocytes restarted their activity. During the first half of thyroid differentiation, the cilia were formed "intracellularly" but during the second half, they differentiated "extracellularly" In the differentiating thyrocytes one cilium per cell was found; however, it could not be excluded that more than one cilium per cell may be formed. These cilia lacked central fibres and therefore they had a 9+0 formula that suggested that they were immotile.
草蛇 Natrix natrix L. 胚胎甲状腺分化伴随纤毛发生过程的超微结构研究。基于这项研究，可以得出结论，纤毛发生发生在两个波中，新的中心粒通过中心粒途径复制。第一波纤毛发生发生在有丝分裂后的甲状腺细胞极化之前。它在发育周期的中途结束。第二波纤毛发生发生在甲状腺细胞极化之后和胚胎甲状腺静止期之前。当完全分化的甲状腺细胞重新开始活动时，这一波纤毛发生在孵化前停止。在甲状腺分化的前半段，纤毛是“细胞内”形成的，但在后半段，它们是“细胞外”分化的。在分化的甲状腺细胞中，每个细胞发现一个纤毛；然而，不能排除每个细胞可能形成多个纤毛。这些纤毛缺乏中央纤维，因此它们具有 9+0 公式，表明它们是不动的。
