Wang Junshuai, Wang Minxin, Huang Yuancheng
Department of Infectious Disease, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Scand J Infect Dis. 2013 Feb;45(2):158-60. doi: 10.3109/00365548.2012.704152. Epub 2012 Jul 25.
Lamivudine, adefovir, telbivudine, and entecavir are nucleoside analogues that can inhibit hepatitis B virus replication and are licensed in China by the Food and Drug Administration. This study presents the cases of 2 patients who were chronically infected with HBV and suffered hepatic failure resulting from withdrawal of telbivudine and adefovir, respectively.
拉米夫定、阿德福韦、替比夫定和恩替卡韦都是核苷类似物,它们能够抑制乙型肝炎病毒复制,且已在中国获得食品药品监督管理局的许可。本研究报告了2例慢性乙型肝炎病毒感染患者的病例,这2例患者分别因停用替比夫定和阿德福韦而导致肝衰竭。