[Limitation of oxidative stress as the main factor of the universal protective properties of melatonin].

Natural hormone melatonin, which is produced by pineal gland and apudocytes of peripheral tissues, has unique and universal protective features against various cerebral and somatic diseases. Melatonin effects may be based on many factors. On the cellular level, the main role in the therapeutic properties of melatonin is played by the antioxidant activity. Much evidence for this hypothesis is presented and reviewed.