Park Bumsoo, Kim Woojung, Jeong Byong Chang, Jeon Seong Soo, Lee Hyun Moo, Choi Han Yong, Seo Seong Il
Department of Urology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
Scand J Urol. 2013 Feb;47(1):10-8. doi: 10.3109/00365599.2012.696137. Epub 2012 Jul 27.
The aim of this study was to compare oncological and functional outcomes of pure laparoscopic radical prostatectomy (LRP) and robotic-assisted laparoscopic radical prostatectomy (RALRP) performed by a single surgeon.
In total, 327 consecutive patients with prostate cancer who underwent radical prostatectomy (144 with LRP and 183 with RALRP) were enrolled. No significant differences were found in prostate-specific antigen level, biopsy Gleason score, clinical T stage or D'Amico risk stratification between the two groups. The operating time was longer in the LRP group (p < 0.001). The RALRP group patients had significantly lower postoperative pain numerical rating scale (NRS) (p = 0.016) and catheter duration (p < 0.001). There were no differences in pathological Gleason score, pathological T stage or positive surgical margin rate. No differences were found in biochemical recurrence-free survival. Postoperative pad-free continence rates revealed a more rapid recovery in the RALRP group, but rates at 12 months were not significantly different. Multivariate analysis showed that the type of surgery was a strong independent factor to predict early postoperative pad use. Postoperative potency rates were not significantly different at 3, 6 and 12 months in patients who underwent nerve-sparing procedures.
LRP and RALRP performed by a single surgeon yielded similar results in terms of safety and oncological outcomes. More favorable outcomes were noted in operating time, pain NRS and catheter duration, as well as urinary continence recovery time. Therefore, RALRP showed more favorable components in terms of postoperative quality of life than LRP.
本研究旨在比较由同一位外科医生实施的单纯腹腔镜根治性前列腺切除术(LRP)和机器人辅助腹腔镜根治性前列腺切除术(RALRP)的肿瘤学及功能学结果。
总共纳入了327例连续接受根治性前列腺切除术的前列腺癌患者(144例行LRP,183例行RALRP)。两组患者在前列腺特异性抗原水平、活检Gleason评分、临床T分期或D'Amico风险分层方面均未发现显著差异。LRP组的手术时间更长(p < 0.001)。RALRP组患者术后疼痛数字评定量表(NRS)得分显著更低(p = 0.016),导尿管留置时间也显著更短(p < 0.001)。病理Gleason评分、病理T分期或手术切缘阳性率方面无差异。生化无复发生存率无差异。术后无尿垫控尿率显示RALRP组恢复更快,但12个月时的控尿率无显著差异。多因素分析表明手术类型是预测术后早期使用尿垫的一个强有力的独立因素。接受保留神经手术的患者在3个月、6个月和12个月时的术后性功能恢复率无显著差异。
由同一位外科医生实施的LRP和RALRP在安全性和肿瘤学结果方面产生了相似的结果。在手术时间、疼痛NRS评分、导尿管留置时间以及尿失禁恢复时间方面观察到了更有利的结果。因此,就术后生活质量而言,RALRP比LRP显示出更有利的方面。