Ozturk C, Ayik F, Oguz E, Ozturk P, Karapolat H, Balcioglu O, Yagdi T, Engin C, Ozbaran M
Department of Physical Therapy and Rehabilitation, Medical Faculty, Ege University, Izmir, Turkey.
Transplant Proc. 2012 Jul-Aug;44(6):1735-7. doi: 10.1016/j.transproceed.2012.05.031.
Ventricular assist device (VAD) application has become an increasingly common method to treatment end-stage heart failure. In this study we evaluated the effect of VAD implantation upon the quality of life among Turkish patients with end-stage heart failure.
Twenty-eight VAD implantation patients included 3 (10.7%) with biventricular support using the Berlin Heart Excor; 15 (53.6%), left ventricular support with the Berlin Heart Excor; and 10 (35.7%), Heartware implantation for left ventricular support. The Minnesota Living with Heart Failure Questionnaire (MLHFQ) and Short Form 36 (SF-36) Health Questionnaire were used to assess changes in the quality of life (QOL).
Of the 28 patients, 2 were females (7.1%) and 26 were males (92.9%) of overall mean age of 44.6 ± 15.3 years (range, 8-66). Preoperative mean score of MLHFQ was significantly improved at 200.4 ± 147.4 days follow-up (72.8 ± 11.5 vs 13.7 ± 10.5; P < .05). SF-36 physical scores and mental scores were improved postoperatively (physical scores, 20.0 ± 24.4 vs 70.2 ± 19.9; mental scores, 38.4 ± 18.8 vs 73.9 ± 15.7; P < .05). No significant relation was observed between the postoperative scores of questionnaires and type of surgery. More improvement in postoperative MLHFQ scores was seen in patients younger than 45 years of age (P = .027). The severity of chronic heart failure (CHF) regressed from New York Heart Association (NYHA) class IV to NYHA class II in 26 and to NYHA class III in 2 patients (P = .000).
The QOL among patients with end-stage heart failure improved dramatically soon after VAD implantation.
心室辅助装置(VAD)的应用已成为治疗终末期心力衰竭越来越常用的方法。在本研究中,我们评估了VAD植入对土耳其终末期心力衰竭患者生活质量的影响。
28例接受VAD植入的患者中,3例(10.7%)使用柏林心脏Excor进行双心室支持;15例(53.6%)使用柏林心脏Excor进行左心室支持;10例(35.7%)植入Heartware进行左心室支持。采用明尼苏达心力衰竭生活问卷(MLHFQ)和简短健康调查问卷36项(SF-36)评估生活质量(QOL)的变化。
28例患者中,女性2例(7.1%),男性26例(92.9%),总体平均年龄为44.6±15.3岁(范围8 - 66岁)。在术后200.4±147.4天的随访中,MLHFQ术前平均得分显著改善(72.8±11.5对13.7±10.5;P < 0.05)。术后SF-36身体评分和精神评分均有所改善(身体评分,20.0±24.4对70.2±19.9;精神评分,38.4±18.8对73.9±15.7;P < 0.05)。问卷术后得分与手术类型之间未观察到显著相关性。45岁以下患者术后MLHFQ得分改善更明显(P = 0.027)。慢性心力衰竭(CHF)的严重程度从纽约心脏协会(NYHA)IV级降至NYHA II级的有26例,降至NYHA III级的有2例(P = 0.000)。
终末期心力衰竭患者在VAD植入后不久生活质量显著改善。