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经导管主动脉瓣植入术 10 周年纪念:当前证据回顾及临床意义。

Transcatheter aortic valve implantation 10-year anniversary: review of current evidence and clinical implications.

机构信息

Columbia University Medical Center and the Cardiovascular Research Foundation, 161 Fort Washington Avenue, 6th Floor, New York, NY 10032, USA.

出版信息

Eur Heart J. 2012 Oct;33(19):2388-98. doi: 10.1093/eurheartj/ehs220. Epub 2012 Jul 31.

Abstract

Surgical aortic valve replacement (SAVR) is currently the standard of care to treat patients with severe symptomatic aortic stenosis (AS) and is generally accepted to alleviate symptoms and prolong survival. Based on the results of randomized trials, transcatheter aortic valve implantation (TAVI) is the new standard of care for patients with symptomatic AS who are deemed 'inoperable'. Debatably, TAVI is also an alternative to SAVR in selected patients who are at high risk but operable. As we approach 10 years of clinical experience with TAVI, with over 50 000 implantations in 40 countries, a review of the current literature and clinical outcomes with this rapidly evolving technology is appropriate.

摘要

外科主动脉瓣置换术(SAVR)目前是治疗严重症状性主动脉瓣狭窄(AS)患者的标准治疗方法,通常被认为可以缓解症状并延长生存期。基于随机试验的结果,经导管主动脉瓣植入术(TAVI)是被认为“不可手术”的有症状 AS 患者的新标准治疗方法。有争议的是,对于高危但可手术的患者,TAVI 也是 SAVR 的替代方法。随着我们在 TAVI 方面积累了近 10 年的临床经验,在 40 个国家完成了超过 50000 例植入手术,对这一快速发展的技术的当前文献和临床结果进行回顾是合适的。

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