磁泳轨迹跟踪磁强计：一种评估亚磁性微粒和细胞磁性特性的新技术。

Magnetophoretic trajectory tracking magnetometry: a new technique for assessing magnetic properties of submagnetic microparticles and cells.

作者信息

Kashevsky B E, Zholud A M, Kashevsky S B

机构信息

A. V. Luikov Heat and Mass Transfer Institute, National Academy of Sciences of Belarus, P. Brovka str., 15, Minsk 220072, Belarus.

出版信息

Rev Sci Instrum. 2012 Jul;83(7):075104. doi: 10.1063/1.4732814.

DOI:10.1063/1.4732814

PMID:22852721

Abstract

We develop a new approach for assessing magnetic properties of submagnetic microparticles and cells, magnetophoretic trajectory tracking magnetometry (MTTM), that employs recording of long 2D trajectories of particle motion in a slot fluid channel caused by the action of crossed gravitational and magnetic forces. The studies are focused on the development of theoretical backgrounds of the method and evaluation of its uncertainty caused by the mutual hydrodynamic entrainment of moving particles. Computerized equipment implementing MTTM technique is described and its performance is illustrated. According to our studies, the new technique can serve a reliable experimental method with analytical qualities.

摘要

我们开发了一种用于评估亚磁性微粒和细胞磁性特性的新方法——磁泳轨迹跟踪磁力测定法（MTTM），该方法通过记录在交叉重力和磁力作用下，微粒在狭缝流体通道中运动的二维长轨迹。研究重点在于该方法理论基础的发展以及对移动粒子相互流体动力夹带所导致的不确定性评估。描述了实现MTTM技术的计算机化设备，并展示了其性能。根据我们的研究，这项新技术可成为一种具有分析特性的可靠实验方法。