Li Xiao-dong, Yan Xue, Chen Li-hua, Tang Hong-juan, Shen Hong-min, Zhou Ying-jie
Department of Obstetrics & Gynecology, Second Hospital, Hebei Medical University, Shijiazhuang 050000, China.
Zhonghua Yi Xue Za Zhi. 2012 May 8;92(17):1187-9.
To assess the significance of intraluminal ultrasound in the diagnosis of developmental status and treatment effect in normal and idiopathic precocious puberty (ICPP) girls.
Endorectal ultrasonography was used to measure the parameters of uterine length, width, thickness, cervix length, ovarian volume and maximum follicular length in normal girls and compare their differences between pre- and post-treatment by gonadotropin-releasing hormone analogues (GnRHa) in idiopathic precocious puberty girls.
The ultrasonic parameters of uterus and ovary in normal girls significantly increased in average 9-year-old girls (1.87 ± 0.58) ml of uterine volume in 9-year-old group vs (1.03 ± 0.24) ml in 7-year-old group; ovarian volume (3.01 ± 2.73) ml of uterine volume in 9-year-old group vs 0.98 ± 0.36 ml in 7-year-old group. They were much greater in ICPP girls and decreased significantly at post-treatment, (1.16 ± 0.19) ml of uterus volume pre-treatment vs (1.02 ± 0.15) ml post-treatment; (2.11 ± 0.48) ml of ovarian volume pre-treatment, (1.72 ± 0.55) ml post-treatment; (1.36 ± 0.25) cm of the biggest follicular diameter pre-treatment, (1.16 ± 0.36) cm post-treatment.
Endosonography is an important tool of evaluating the development status and treatment effect in normal and ICPP girls.
评估腔内超声在诊断正常及特发性中枢性性早熟(ICPP)女童发育状况及治疗效果中的意义。
采用直肠内超声测量正常女童子宫长度、宽度、厚度、宫颈长度、卵巢体积及最大卵泡长度等参数,并比较特发性中枢性性早熟女童在促性腺激素释放激素类似物(GnRHa)治疗前后上述参数的差异。
正常女童子宫及卵巢的超声参数在平均9岁女童中显著增加,9岁组子宫体积平均为(1.87±0.58)ml,7岁组为(1.03±0.24)ml;9岁组卵巢体积(3.01±2.73)ml,7岁组为0.98±0.36 ml。ICPP女童的上述参数更高,治疗后显著降低,治疗前子宫体积(1.16±0.19)ml,治疗后为(1.02±0.15)ml;治疗前卵巢体积(2.11±0.48)ml,治疗后为(1.72±0.55)ml;治疗前最大卵泡直径(1.36±0.25)cm,治疗后为(1.16±0.36)cm。
腔内超声检查是评估正常及ICPP女童发育状况及治疗效果的重要工具。