Williams Bryce J D, Isom Alex, Laureano Filho José R, O'Ryan Felice S
Department of Oral and Maxillofacial Surgery, Highland General Hospital and Division of Maxillofacial Surgery, Kaiser Permanente Oakland Medical Center, Oakland, CA 94611, USA.
J Oral Maxillofac Surg. 2013 Feb;71(2):343-50. doi: 10.1016/j.joms.2012.05.010. Epub 2012 Aug 9.
To examine nasal airway function using a disease-specific quality-of-life survey instrument in subjects undergoing Le Fort I osteotomy without simultaneous rhinosurgical procedures.
We conducted a prospective cohort study of nasal airway function in consecutive Le Fort I osteotomy patients, who had not received simultaneous rhinosurgical procedures, between 2007 and 2008 at Kaiser Permanente Oakland Medical Center. We administered the Nasal Obstruction Symptom Evaluation (NOSE) survey before and 3 months after surgery. Clinical and radiographic examinations were performed, and the relevant medical and demographic factors were analyzed.
The initial study sample comprised 55 patients, of whom 5 were excluded. Of the remaining 50 patients (median age 21 years, 60% women), the maxilla was advanced (median 4 mm, interquartile range 3 to 5) with minimal vertical change. During the follow-up period (median 5.5 months), significant improvement was seen in the NOSE scores for the cohort, with a median decrease of 10 units (P = .0005). Patients with moderate nasal obstruction (preoperative NOSE score >25) had the greatest improvement (P < .001). Those with severe nasal obstruction (preoperative NOSE score >50) improved, however, this did not reach statistical significance (P < .0625). The NOSE scores worsened in 10 patients; of these, 6 had minimal change. However, 4 had significant worsening, with 2 having symptomatic complaints. No predictor variables were identified in this small subgroup; however, individual case analyses revealed 1 subject with postoperative turbinate inflammation on the side of maxillary segmentalization and 1 had nasal septal buckling.
Our overall findings have suggested that nasal airway function improved after maxillary advancement and that subjects with greater preoperative NOSE scores (>25) were more likely to experience relief of nasal obstructive symptoms.
使用特定疾病的生活质量调查问卷,对未同时接受鼻外科手术的接受勒福Ⅰ型截骨术的患者的鼻气道功能进行评估。
我们于2007年至2008年在奥克兰凯撒医疗中心对连续的未同时接受鼻外科手术的勒福Ⅰ型截骨术患者的鼻气道功能进行了一项前瞻性队列研究。我们在手术前和术后3个月进行了鼻阻塞症状评估(NOSE)调查。进行了临床和影像学检查,并分析了相关的医学和人口统计学因素。
最初的研究样本包括55名患者,其中5名被排除。其余50名患者(中位年龄21岁,60%为女性),上颌骨向前推进(中位4mm,四分位间距3至5),垂直变化最小。在随访期间(中位5.5个月),该队列的NOSE评分有显著改善,中位数下降10分(P = .0005)。中度鼻阻塞患者(术前NOSE评分>25)改善最大(P < .001)。重度鼻阻塞患者(术前NOSE评分>50)有所改善,但未达到统计学意义(P < .0625)。10名患者的NOSE评分恶化;其中6名变化最小。然而,4名有显著恶化,2名有症状性主诉。在这个小亚组中未发现预测变量;然而,个别病例分析显示1名患者在上颌骨分段侧有术后鼻甲炎症,1名有鼻中隔弯曲。
我们的总体研究结果表明,上颌骨前移后鼻气道功能得到改善,术前NOSE评分较高(>25)的患者更有可能缓解鼻阻塞症状。