Shen Hao, Wang Qiao-jie, Zhang Xian-long, Jiang Yao, Wang Qi, Chen Yun-su, Shao Jun-jie
Department of Orthopaedic Surgery, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiaotong University, Shanghai 200233, China.
Zhonghua Wai Ke Za Zhi. 2012 May;50(5):402-6.
To determine the clinical outcomes of two-staged cementless revision arthroplasty for the treatment of deep periprosthetic infection after total hip arthroplasty.
Twenty-three patients with deep periprosthetic infection treated with a standard protocol of two-staged cementless revision hip arthroplasty were enrolled in this study. There were 9 male patients and 14 female patients with an average age of 64 years (range, 52-78 years). In all cases, antibiotics-loaded cement spacers were implanted after removal of all the prosthetic components and thorough debridements had been done. All patients had a minimum of 2 weeks of intravenous antibiotics followed by 4 weeks of oral antibiotics after implant removal. After a mean interval of 6.7 months (3-28 months), revision arthroplasties were carried out with cementless femoral components followed by 2 weeks of intravenous antibiotics and 4 weeks of oral antibiotics.
The mean follow-up period was (4.3±3.5) years. There were 2 cases of recurrent infections in this study. Intraoperative periprosthetic fractures were observed in 3 patients. One patient had dislocation of the implanted spacer during the interval period and 2 patients had hip dislocation after reimplantation. Mild subsidence of femoral component occurred in 1 patient. There were no cases of loosening of femoral components and cementless acetabular components in patients without infection recurrence. The Harris hip score increased from a preoperative mean of 36±13 to 85±13 at 12 months after reimplantation.
Using cementless prostheses in two-staged revisions of hip periprosthetic infections can provide low rate of infection recurrence and good implant stability, but cautions must be taken when treating patients with infection caused by multidrug-resistant organisms.
确定两阶段非骨水泥型翻修关节成形术治疗全髋关节置换术后深部假体周围感染的临床疗效。
本研究纳入23例接受标准两阶段非骨水泥型翻修髋关节置换术治疗深部假体周围感染的患者。其中男性9例,女性14例,平均年龄64岁(范围52 - 78岁)。所有病例均在取出所有假体组件并彻底清创后植入含抗生素骨水泥间隔物。所有患者在取出植入物后至少接受2周静脉抗生素治疗,随后口服抗生素4周。平均间隔6.7个月(3 - 28个月)后,进行非骨水泥型股骨组件翻修关节成形术,术后再接受2周静脉抗生素治疗和4周口服抗生素治疗。
平均随访期为(4.3±3.5)年。本研究中有2例复发性感染。3例患者术中出现假体周围骨折。1例患者在间隔期植入的间隔物发生脱位,2例患者再植入后出现髋关节脱位。1例患者股骨组件轻度下沉。未发生感染复发的患者中,股骨组件和非骨水泥型髋臼组件均无松动病例。Harris髋关节评分从术前平均36±13分提高到再植入后12个月时的85±13分。
在髋关节假体周围感染的两阶段翻修中使用非骨水泥假体可提供较低的感染复发率和良好的植入稳定性,但在治疗由多重耐药菌引起感染的患者时必须谨慎。