Department of General, Thoracic, and Transplant Surgery, University of Schleswig-Holstein, Campus Kiel, Kiel, Germany.
Surgery. 2013 Feb;153(2):189-99. doi: 10.1016/j.surg.2012.06.027. Epub 2012 Aug 11.
In adult live donor liver transplantation, postoperative venous congestion of graft and remnant livers can lead to life-threatening complications. The purpose of this study was to evaluate the safety and benefits of our 3-dimensional, computed tomographic, computer-assisted donor hepatectomy using the "carving" partitioning technique.
Eighty-three consecutive adult live donor liver transplantations were performed based on data obtained from individualized preoperative 3-dimensional, computed tomographic reconstructions and virtual graft hepatectomies.
There were 71 right and 12 left grafts. Small grafts (graft volume body weight ratio, <1.0) were used in 20 cases. We observed no clinically important differences in postoperative function between right and left grafts. Four recipients developed lethal small-for-size syndrome. Reversible small-for-size syndrome was observed in a right graft recipient and in 2 right graft donors.
Preoperative 3-dimensional, computed tomographic, computer-assisted planning using virtual liver partitioning allowed for: (1) an individualized carving technique based on specific donor anatomic characteristics, (2) donor safety based on individualized patterns of venous outflow, and (3) optimized drainage of the medial area of the graft based on the preferential inclusion of the middle hepatic vein.
成人活体供肝移植术后,供肝和残余肝脏的静脉淤血可能导致危及生命的并发症。本研究旨在评估我们采用“雕刻”分区技术的三维 CT 计算机辅助供肝切除术的安全性和优势。
根据个体化术前三维 CT 重建和虚拟肝切除术获得的数据,连续进行了 83 例成人活体供肝移植。
右肝 71 例,左肝 12 例。20 例采用小体积供肝(供肝体积与受者体重比<1.0)。右肝和左肝的术后功能无明显差异。4 例受体发生致命性小肝综合征。1 例右肝受体和 2 例右肝供者发生可逆性小肝综合征。
术前采用三维 CT 计算机辅助规划,通过虚拟肝脏分区实现个体化的“雕刻”技术,基于供肝静脉流出模式保证供者安全,同时根据中肝静脉的优势,优化供肝内侧区域的引流。