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子宫肌层中的促黄体生成素/人绒毛膜促性腺激素受体及其在子宫运动中的作用。

Luteinizing hormone/human chorionic gonadotropin receptors in myometrium and their role in uterine motility.

作者信息

Ziecik A J

机构信息

Institute of Animal Physiology, University of Agriculture and Technology, Olsztyn, Poland.

出版信息

Arch Immunol Ther Exp (Warsz). 1990;38(1-2):141-4.

PMID:2288470
Abstract

The object of this paper is the existence of LH/hCG receptors in female uterine tissue. Specific and high-affinity binding sites for LH are present in the pig and rabbit uterus. Estradiol promoted the synthesis of LH receptors in porcine myometrium. Stimulation of LH receptors with hCG in estrogen-primed tissue had a quiescence effect on myometrial contractility in vitro. The physiological role of uterine LH receptors in maintenance of myometrial quiescence is discussed.

摘要

本文的研究对象是女性子宫组织中促黄体生成素/人绒毛膜促性腺激素(LH/hCG)受体的存在情况。猪和兔的子宫中存在LH的特异性高亲和力结合位点。雌二醇可促进猪子宫肌层中LH受体的合成。在雌激素预处理的组织中,用hCG刺激LH受体对体外子宫肌层收缩性有静息作用。文中讨论了子宫LH受体在维持子宫肌层静息中的生理作用。

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