Department of Chemistry, Organic and Bioorganic Chemistry, University of Graz, Graz, Austria.
Angew Chem Int Ed Engl. 2012 Sep 3;51(36):9156-9. doi: 10.1002/anie.201204683. Epub 2012 Aug 9.
Driving the machinery: A biocatalytic redox-neutral cascade for the preparation of terminal primary amines from primary alcohols at the expense of ammonia has been established in a one-pot one-step method. Applying this artificial biocatalyst network, long-chain 1,ω-alkanediols were converted into diamines, which are building blocks for polymers, in up to 99 % conversion.
在一锅一步法中建立了一种生物催化氧化还原中性级联反应，从伯醇中制备末端伯胺，代价是氨。应用这种人工生物催化剂网络，长链 1,ω-烷二醇可转化为二胺，二胺是聚合物的构建块，转化率高达 99%。
