Department of Surgery, Vascular Surgery Unit, Medical School, University of Ioannina, Greece.
J Endovasc Ther. 2012 Aug;19(4):504-11. doi: 10.1583/JEVT-12-3886R.1.
To review the literature on the endovascular management of external carotid artery (ECA) disease.
A review was conducted of the English-language medical literature from 1985 to 2011 using PubMed, OVID, and EMBASE databases to find all studies involving endovascular management of ECA stenosis. The search identified 21 reports describing endovascular repair of ECA lesions encompassing 56 patients (35 men; mean age 62.6±10.5 years) and 58 arteries.
The majority of patients (91.1%) were reported to have ipsilateral ICA occlusion, while 55.6% of patients were symptomatic. In the 56 patients, 33 arteries received stents primarily, while 25 had primary balloon angioplasty; 52 cases involved endovascular repair of ECA stenosis, while 4 patients with a normal ECA had a covered stent deployed to exclude the ICA stump. The technical success rate was 98.3%. During the first 30 days after the procedure, 1 (1.8%) stroke was reported, while 5 (8.9%) transient ischemic attacks were also described. During a follow-up period spanning an average 23.8±18.3 months, none of the patients experienced any clinical cerebrovascular event. Two (3.4%) dilated ECAs developed restenosis, while 1 (1.7%) ECA stent occluded at 6 months.
Endovascular repair of ECA appears to have low rates of perioperative stroke or death but a high rate of TIAs. The appropriate type of stent and the use of embolic protection need to be established. In the endovascular era, despite the limited data available, this therapeutic approach could be considered a reasonable alternative to conventional open repair, especially in patients with ipsilateral ICA occlusion and concomitant contralateral carotid stenosis or occlusion, an insufficient circle of Willis, and other significant comorbidities.
回顾关于颈外动脉(ECA)疾病血管内治疗的文献。
通过检索 1985 年至 2011 年的英文医学文献,使用 PubMed、OVID 和 EMBASE 数据库,查找所有涉及 ECA 狭窄血管内治疗的研究。该检索共确定了 21 项描述 ECA 病变血管内修复的报告,共纳入 56 例患者(35 例男性;平均年龄 62.6±10.5 岁)和 58 条动脉。
大多数患者(91.1%)同侧颈内动脉闭塞,55.6%的患者有症状。56 例患者中,33 条动脉主要接受支架治疗,25 条动脉接受单纯球囊血管成形术;52 例为 ECA 狭窄血管内修复,4 例正常 ECA 患者行带膜支架置入以闭塞颈内动脉残端。技术成功率为 98.3%。术后 30 天内,1 例(1.8%)发生卒中,5 例(8.9%)发生短暂性脑缺血发作。平均随访 23.8±18.3 个月期间,无患者发生任何临床脑血管事件。2 例(3.4%)扩张的 ECA 发生再狭窄,1 例(1.7%)ECA 支架在 6 个月时闭塞。
ECA 血管内修复的围手术期卒中或死亡率较低,但短暂性脑缺血发作发生率较高。需要确定合适的支架类型和使用栓塞保护装置。在血管内治疗时代,尽管现有数据有限,但这种治疗方法可被视为传统开放修复的合理替代方法,尤其适用于同侧颈内动脉闭塞且伴有对侧颈动脉狭窄或闭塞、Willis 环不足和其他重大合并症的患者。