Abbruzzese G, Dall'Agata D, Morena M, Reni L, Trivelli G, Favale E
Department of Neurology, University of Genoa, Italy.
Electroencephalogr Clin Neurophysiol Suppl. 1990;41:145-8. doi: 10.1016/b978-0-444-81352-7.50018-2.
The effects of changing the stimulus presentation rate on early parietal (N20-P25) and frontal (P22-N30) somatosensory potentials (SEPs), evoked by median nerve stimulation, were investigated in 15 normal subjects. Stimuli were presented at 0.1, 0.4, 1.0, 4.0 and 10/sec. Only minor latency changes, mainly for the frontal P22 component, were observed when the stimulus rate was increased up to 10/sec: while the frontal P22-N30 complex was more rapidly and severely reduced in amplitude than the parietal N20-P25 complex. The differential effects of stimulus presentation rate on early frontal and parietal SEPs support the hypothesis of separate neural generators and suggest that the choice of the stimulation frequency may be critical for the interpretation of diagnostic SEP studies.
在15名正常受试者中，研究了改变刺激呈现速率对正中神经刺激诱发的早期顶叶（N20 - P25）和额叶（P22 - N30）体感诱发电位（SEP）的影响。刺激以0.1、0.4、1.0、4.0和10次/秒的频率呈现。当刺激速率增加到10次/秒时，仅观察到轻微的潜伏期变化，主要是额叶P22成分；而额叶P22 - N30复合波在幅度上比顶叶N20 - P25复合波更快、更严重地降低。刺激呈现速率对早期额叶和顶叶SEP的不同影响支持了独立神经发生器的假说，并表明刺激频率的选择对于诊断性SEP研究的解释可能至关重要。
