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使用磁共振断层合成(MRT)技术的3D成像。

3D imaging using magnetic resonance tomosynthesis (MRT) technique.

作者信息

Kim Min-Oh, Zho Sang-Young, Kim Dong-Hyun

机构信息

Department of Electrical and Electronic Engineering, Yonsei University, Seodaemun-gu, Seoul 120-749, South Korea.

出版信息

Med Phys. 2012 Aug;39(8):4733-41. doi: 10.1118/1.4737111.

Abstract

PURPOSE

To introduce an alternative approach to three-dimensional (3D) magnetic resonance (MR) imaging using a method that is similar to x-ray tomosynthesis.

METHODS

Variable angle tilted-projection images are acquired using a multiple-oblique view (MOV) pulse sequence. Reconstruction is performed using three methods similar to that of x-ray tomosynthesis, which generate a set of tomographic images with multiple 2D projection images. The reconstruction algorithm is further modified to reformat to the practical imaging situations of MR. The procedure is therefore termed magnetic resonance tomosynthesis (MRT). To analyze the characteristics of MRT, simulations are performed. Phantom and in vivo experiments were done to suggest potential applications.

RESULTS

Simulation results show anisotropic features that are structurally dependent in terms of resolution. Partial blurrings along slice direction were observed. In phantom and in vivo experiments, the reconstruction performance is particularly noticeable in the low SNR case where improved images with lower noise are obtained. Reformatted reconstruction using thinner slice thickness and∕or extended field-of-view can increase spatial resolution partially and alleviate slice profile imperfection.

CONCLUSIONS

Results demonstrate that MRT can generate adequate 3D images using the MOV images. Various reconstruction methods in tomosynthesis were readily adapted, while allowing other tomosynthesis reconstruction algorithms to be incorporated. A reformatted reconstruction process was incorporated for applications relevant to MR imaging.

摘要

目的

介绍一种类似于X射线断层合成的方法用于三维(3D)磁共振(MR)成像的替代方法。

方法

使用多角度倾斜投影图像采集采用多斜视图(MOV)脉冲序列。使用三种类似于X射线断层合成的方法进行重建,该方法通过多个二维投影图像生成一组断层图像。进一步修改重建算法以适应MR的实际成像情况。因此该过程被称为磁共振断层合成(MRT)。为分析MRT的特性,进行了模拟。进行了体模和体内实验以表明潜在应用。

结果

模拟结果显示出在分辨率方面结构相关的各向异性特征。观察到沿切片方向的部分模糊。在体模和体内实验中,在低信噪比情况下重建性能尤为显著,可获得噪声更低的改进图像。使用更薄的切片厚度和/或扩展视野进行重新格式化重建可部分提高空间分辨率并减轻切片轮廓缺陷。

结论

结果表明MRT可以使用MOV图像生成足够的3D图像。断层合成中的各种重建方法易于采用,同时允许纳入其他断层合成重建算法。纳入了重新格式化重建过程以用于与MR成像相关的应用。

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