Ruissen C J, von Drongelen M M, Hoogland H J, Jager W, Hoeks A P
Department of Biophysics, University of Limburg, Maastricht, The Netherlands.
Gynecol Obstet Invest. 1990;30(4):212-6. doi: 10.1159/000293272.
In 30 uncomplicated singleton pregnancies, varying in duration between 24 and 40 weeks, the variability of the flow velocity waveform (FVW) along the course of the umbilical artery was investigated. Blood flow velocities were recorded at 4 locations in the vessel: within the fetal abdomen, 0-5 cm from the origin of the umbilical cord, in the free-floating part, and 0-5 cm from its insertion in the placenta. From the Doppler signals recorded, the pulsatility index (PI) and a parameter for the frequency distribution index (FDI) were calculated. PI values differed among the locations, but no unequivocal tendency could be demonstrated. Statistical analysis, including multiple regression analysis for maternal and menstrual age and fetal heart rate, showed no significant difference in PI and FDI values for any of the 4 locations. It can be concluded that in uncomplicated pregnancies, possible changes in FVW (quantified by PI) along the course of the umbilical artery have no clinical relevance. Therefore, standardization for the sampling site when measuring PI in this vessel seems to be unnecessary.
在30例孕周为24至40周的单胎无并发症妊娠中，研究了脐动脉全程血流速度波形（FVW）的变异性。在血管的4个位置记录血流速度：胎儿腹部内、距脐带起点0 - 5厘米处、游离部分以及距胎盘插入处0 - 5厘米处。根据记录的多普勒信号，计算搏动指数（PI）和频率分布指数（FDI）参数。PI值在不同位置有所不同，但未显示出明确的趋势。包括对母亲年龄、月经年龄和胎儿心率进行多元回归分析在内的统计分析表明，4个位置中任何一个位置的PI和FDI值均无显著差异。可以得出结论，在无并发症妊娠中，脐动脉全程FVW（以PI量化）的可能变化无临床意义。因此，在该血管中测量PI时似乎无需对采样部位进行标准化。
