van Riet T C T, Frank M H, Hoeben K A, de Lange J
Uit de afdeling Mondziekten, Kaak- en Aangezichtschirurgie, Amsterdam.
Ned Tijdschr Tandheelkd. 2012 Jul-Aug;119(7-8):368-72. doi: 10.5177/ntvt.2012.07/08.11245.
Symptoms of familial hypophosphatemic rickets are growth retardation, the formation of O- or X-legs, pain of the joints, spontaneous dental abscesses, and delayed tooth eruption. The dental symptoms are predominantly attributable to the demineralization of dentin. In absence of adequate preventive measurements,familial hypophosphatemic rickets may lead to spontaneous pulpal necrosis. The prophylactic application of occlusal sealants might be effective in preventing abscess formation.