Rodrigues Maura Calixto Cecherelli de, Mello Rosane Reis de, Silva Kátia Silveira da, Carvalho Márcia Lazaro de
Doutora em Ciências pela Fundação Oswaldo Cruz (FIOCRUZ). Médica Pediatra coordenadora do Núcleo de Atenção Interdisciplinar ao Recém-nascido de Risco da Maternidade Leila Diniz-Hospital Municipal Lourenço Jorge, Rio de Janeiro RJ, Brazil.
Arq Neuropsiquiatr. 2012 Aug;70(8):583-9. doi: 10.1590/s0004-282x2012000800005.
The purpose was to analyze factors associated with cognitive impairment in very low birth weight (VLBW) children born preterm. A prospective cohort of 65 VLBW children was assessed at the age of eight years using the Wechsler Intelligence Scale for Children. A model for the relationship of variables with the cognitive impairment outcome attributed hierarchical levels: distal (socioeconomic variables), intermediate I and II (perinatal and neonatal variables, post-neonatal variables) and proximal (child health and psychosocial stimulation). A multivariate logistic regression was performed. In the multivariate hierarchical logistic regression, the maternal education (OR=0.77, 95%CI 0.63-0.94) and number of prenatal visits (OR=0.73, 95%CI 0.54-0.99) showed a protective association, but the male (OR=7.3, 95%CI 1.54-35.3) was associated with worse results. The VLBW children cognitive performance in the age of eight years benefits from more educated mothers, better prenatal care, and the baby gender as female.
目的是分析早产极低出生体重（VLBW）儿童认知障碍的相关因素。对65名VLBW儿童的前瞻性队列在8岁时使用韦氏儿童智力量表进行评估。一个关于变量与认知障碍结果关系的模型赋予了层次水平：远端（社会经济变量）、中间I和II（围产期和新生儿变量、新生儿后期变量）以及近端（儿童健康和心理社会刺激）。进行了多变量逻辑回归分析。在多变量层次逻辑回归中，母亲教育程度（OR = 0.77，95%CI 0.63 - 0.94）和产前检查次数（OR = 0.73，95%CI 0.54 - 0.99）显示出保护关联，但男性（OR = 7.3，95%CI 1.54 - 35.3）与较差结果相关。8岁的VLBW儿童的认知表现受益于母亲受教育程度更高、更好的产前护理以及女性婴儿性别。
