Department of Urology, CHA Bundang Medical Center, CHA University, Seongnam, Korea.
Urology. 2012 Oct;80(4):784-9. doi: 10.1016/j.urology.2012.06.032. Epub 2012 Aug 15.
To evaluate stone diameter and ureteral dilation using computerized tomography as a predictor of ureteral stone expulsion after medical expulsive therapy.
We retrospectively reviewed the records of 328 patients with symptomatic ureteral stones <10 mm on axial computerized tomography images, who were treated with alpha blockers for 2 weeks. Computerized tomography scans were also performed 2 weeks after medical expulsive therapy to confirm ureteral stone expulsion. Patients were divided into upper ureteral stones and lower ureteral stones above and below the iliac vessels, respectively. Transverse stone diameter and longitudinal stone diameter were defined as the largest stone diameter determined on the axial and coronal computerized tomography images, respectively. Ureteral diameter was determined on one computerized tomography slice proximal to each ureteral stone on axial computerized tomography images, and the ratio of ureter-to-stone diameter was defined as ureteral diameter divided by transverse stone diameter.
Among 328 patients, the stone expulsion rate was 44.1% in 145 upper ureteral stones and 69.4% in 183 lower ureteral stones. Transverse stone diameter, longitudinal stone diameter, ureteral diameter, and the ratio of ureter-to-stone diameter were significantly lower in patients with ureteral stone expulsion in upper ureteral stones and lower ureteral stones (P < .001 for all parameters). Logistic regression analysis revealed that only longitudinal stone diameter was a significant predictor of stone expulsion in patients with upper ureteral stones (odds ratio 0.580, P = .040) and lower ureteral stones (odds ratio 0.415, P = .012).
Longitudinal stone diameter was a significant predictor of stone expulsion in patients with upper ureteral stones and lower ureteral stones after medical expulsive therapy. Measurement of stone diameters in coronal reconstruction may help to better choose a patient who is suitable for medical expulsive therapy.
通过计算机断层扫描评估结石直径和输尿管扩张程度,以预测药物排石治疗后输尿管结石的排出情况。
我们回顾性分析了 328 例轴向计算机断层扫描图像中直径<10mm 的有症状输尿管结石患者的资料,这些患者接受了 2 周的α受体阻滞剂治疗。药物排石治疗 2 周后,再次进行计算机断层扫描以确认输尿管结石是否排出。患者分为上段输尿管结石和下段输尿管结石,分别位于髂血管以上和以下。横径和纵径分别定义为轴向和冠状计算机断层扫描图像上最大结石直径。输尿管直径在轴向计算机断层扫描图像上每个输尿管结石近端的一个层面上确定,输尿管与结石的比值定义为输尿管直径除以横径。
在 328 例患者中,145 例上段输尿管结石中有 44.1%的患者结石排出,183 例下段输尿管结石中有 69.4%的患者结石排出。上段输尿管结石和下段输尿管结石中,结石排出患者的横径、纵径、输尿管直径和输尿管与结石的比值均显著低于未排出结石的患者(所有参数 P<0.001)。Logistic 回归分析显示,仅纵径是上段输尿管结石(优势比 0.580,P=0.040)和下段输尿管结石(优势比 0.415,P=0.012)结石排出的显著预测因素。
在药物排石治疗后,上段输尿管结石和下段输尿管结石的纵径是结石排出的显著预测因素。冠状位重建的结石直径测量可能有助于更好地选择适合药物排石治疗的患者。