Burton J H, Powers B E, Biller B J
Department of Clinical Sciences, Animal Cancer Center, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO, USA.
Vet Comp Oncol. 2014 Sep;12(3):198-204. doi: 10.1111/j.1476-5829.2012.00351.x. Epub 2012 Aug 21.
With the exception of solar-induced dermal hemangiosarcoma (HSA), the biologic behaviour of canine HSA is characterised by rapid tumour growth, a high metastatic rate and short survival times. Outcome of dogs with HSA of the tongue has not been previously reported. The purpose of this study was to assess outcome and prognostic factors in dogs with lingual HSA. Clinical data was collected retrospectively and histopathology was reviewed for 20 dogs. Median progression free survival was 524 days and the median overall survival time was 553 days. All dogs had low or intermediate grade tumours; most tumours were small and located on the ventral surface of the tongue. Prognostic factors significantly associated with increased survival included small tumour size and absence of clinical signs of an oral mass at the time of diagnosis. Dogs with HSA confined to the tongue may have a better prognosis compared with HSA in other organs.
除了日光性皮肤血管肉瘤(HSA)外,犬类HSA的生物学行为特征为肿瘤生长迅速、转移率高且存活时间短。此前尚未报道过患有舌部HSA的犬的预后情况。本研究的目的是评估患有舌部HSA的犬的预后及预后因素。对20只犬的临床数据进行了回顾性收集,并对组织病理学进行了复查。无进展生存期的中位数为524天,总生存期的中位数为553天。所有犬均患有低级别或中级别的肿瘤;大多数肿瘤较小,位于舌腹面。与生存期延长显著相关的预后因素包括肿瘤体积小以及诊断时无口腔肿物的临床体征。与其他器官的HSA相比,局限于舌部的HSA犬可能预后更好。