Cole Eye Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA.
J Cataract Refract Surg. 2012 Sep;38(9):1694-7. doi: 10.1016/j.jcrs.2012.07.012.
A 54-year-old woman who had photorefractive keratectomy (PRK) more than 10 years earlier presented with a history of being hit in the eye by a tree branch and developing blurred vision a short time later. The corrected visual acuity was 20/100 with localized grade 3 stromal haze. The haze intensified despite initial response to corticosteroids and cyclosporine, and treatment with phototherapeutic keratectomy and 0.02% mitomycin-C (MMC) was effective in restoring corneal clarity and normal vision. Late-onset stromal scar can be triggered by trauma years after PRK. Phototherapeutic keratectomy with MMC can be an effective treatment for late-onset scar. Persistent haze or scar after trauma if PRK had not been performed previously is exceedingly rare.
一位 54 岁的女性，在 10 多年前接受了光折射性角膜切削术（PRK），之后因眼部被树枝击中，不久后视力变得模糊而就诊。矫正视力为 20/100，伴有局部 3 级基质混浊。尽管最初对皮质类固醇和环孢素治疗有反应，但混浊仍加重，光动力疗法角膜切削术联合 0.02%丝裂霉素 C（MMC）治疗可有效恢复角膜透明度和正常视力。PRK 多年后，迟发性基质瘢痕可由创伤引发。MMC 光动力疗法角膜切削术是治疗迟发性瘢痕的有效方法。如果之前未行 PRK，创伤后持续混浊或瘢痕极为罕见。
