用于调节蛋白酪氨酸磷酸酶和SH2结构域高度特异性标记的基于苯甲酰膦酸酯的光活性磷酸肽模拟物。 - Suppr

Benzoylphosphonate-based photoactive phosphopeptide mimetics for modulation of protein tyrosine phosphatases and highly specific labeling of SH2 domains.

作者信息

Horatscheck André, Wagner Stefan, Ortwein Jutta, Kim Boo Geun, Lisurek Michael, Beligny Samuel, Schütz Anja, Rademann Jörg

机构信息

Abteilung für Medizinische Chemie, Leibniz-Institut für Molekulare Pharmakologie, Robert-Rössle-Strasse 10, 13125 Berlin, Germany.

出版信息

Angew Chem Int Ed Engl. 2012 Sep 10;51(37):9441-7. doi: 10.1002/anie.201201475. Epub 2012 Aug 21.

DOI:10.1002/anie.201201475

PMID:22907897

Abstract

摘要

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Benzoylphosphonate-based photoactive phosphopeptide mimetics for modulation of protein tyrosine phosphatases and highly specific labeling of SH2 domains.

Angew Chem Int Ed Engl. 2012 Sep 10;51(37):9441-7. doi: 10.1002/anie.201201475. Epub 2012 Aug 21.

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Benzoylphosphonate-based photoactive phosphopeptide mimetics for modulation of protein tyrosine phosphatases and highly specific labeling of SH2 domains.

作者信息

Horatscheck André, Wagner Stefan, Ortwein Jutta, Kim Boo Geun, Lisurek Michael, Beligny Samuel, Schütz Anja, Rademann Jörg

机构信息

Abteilung für Medizinische Chemie, Leibniz-Institut für Molekulare Pharmakologie, Robert-Rössle-Strasse 10, 13125 Berlin, Germany.

出版信息

Angew Chem Int Ed Engl. 2012 Sep 10;51(37):9441-7. doi: 10.1002/anie.201201475. Epub 2012 Aug 21.

DOI:10.1002/anie.201201475

PMID:22907897

Abstract

摘要

Benzoylphosphonate-based photoactive phosphopeptide mimetics for modulation of protein tyrosine phosphatases and highly specific labeling of SH2 domains.

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Benzoylphosphonate-based photoactive phosphopeptide mimetics for modulation of protein tyrosine phosphatases and highly specific labeling of SH2 domains.

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