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[色素性青斑。组织学结构与发病机制假说]

[Pigmented livedo. Histologic design and pathogenetic hypothesis].

作者信息

Bilancini S, Gallo P, Bernucci P, d'Amati G, Lucchi M

机构信息

Centre d'études des Maladies vasculaires, Frosinone, Italie.

出版信息

Phlebologie. 1990 Jul-Oct;43(3):477-83; discussion 483-4.

PMID:2290866
Abstract

Pigmented livedo is a frequently encountered disease. It occurs as an ochre reticular membrane which does not disappear when the limb is raised. It is characteristic in persons who already have livido reticularis and who expose themselves for several hours every day to the heat from chimneys or foot-warmers. We wanted to study the histological context of this disease in a group of female patients that we kept under observation. The data that we compiled showed that it is due to lymphocytic vasculitis accompanied by atrophy of the epidermis, hyperpigmentation of the basal keratinocytes and telangiectasia. Our pathogenetic hypothesis is that it involves vasculitis "a calore", with atrophy of the epidermis, telangiectasia and melanoid pigmentation, which is the cause of the characteristic brown pigmentation.

摘要

色素性青斑是一种常见疾病。它表现为一种赭色网状斑,肢体抬高时不会消失。在已有网状青斑且每天暴露于烟囱或暖脚器产生的热量中数小时的人群中较为典型。我们想在一组接受观察的女性患者中研究这种疾病的组织学情况。我们收集的数据表明,它是由淋巴细胞性血管炎引起的,伴有表皮萎缩、基底角质形成细胞色素沉着和毛细血管扩张。我们的发病机制假说是,它涉及“受热性”血管炎,伴有表皮萎缩、毛细血管扩张和黑素样色素沉着,这是特征性棕色色素沉着的原因。

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