Xiao Shu-Hua, Xue Jian
National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention, Shanghai 200025, China.
Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi. 2012 Apr 30;30(2):131-8, 145.
In recent years, antimalarial drug mefloquine, an amino alcohol compound, has been found to exhibit potential effect against schistosomes. The feature of antischistosomal properties of mefloquine is that the drug possesses similar killing effect against various development stages of juvenile and adult schistosomes. This paper summarizes the recent three years' progress in experimental studies of mefloquine against schistosomes and other helminthes.
近年来,抗疟药物甲氟喹,一种氨基醇化合物,已被发现对血吸虫具有潜在作用。甲氟喹抗血吸虫特性的特点是该药物对幼虫和成虫血吸虫的各个发育阶段具有相似的杀伤作用。本文总结了近三年甲氟喹抗血吸虫及其他蠕虫实验研究的进展。