Maier G, Blech M, Droese M, Ringert R H
Urologische Klinik, Georg-August-Universität Göttingen.
Urologe A. 1990 Nov;29(6):330-3.
In a retrospective study in which 273 patients with histologically proven carcinoma of the urinary bladder had been examined by performed cytological and flow cytometric analysis carried out in parallel, the diagnostic yield of flow cytometry was compared with the result of urinary cytology. Urinary cytology and flow cytometry made it possible to detect histologically proven transitional cell carcinoma (TCC) in 60% and 64%, respectively. Combination of the two methods increased the diagnostic yield to 76%. An increase in the diagnostic yield was seen especially for well-differentiated TCC, from 34% to 51%. In spite of this improvement, the combination of flow cytometry with urinary cytology did not mean fewer endoscopic investigations were needed in view of the persisting substantial diagnostic deficit in well-differentiated TCC.
在一项回顾性研究中，对273例经组织学证实的膀胱癌患者同时进行了细胞学和流式细胞术分析，比较了流式细胞术的诊断率与尿液细胞学检查结果。尿液细胞学检查和流式细胞术分别能检测出60%和64%经组织学证实的移行细胞癌（TCC）。两种方法联合使用可将诊断率提高到76%。尤其是对于高分化TCC，诊断率从34%提高到了51%。尽管有这种改善，但鉴于高分化TCC中仍存在大量诊断不足的情况，流式细胞术与尿液细胞学联合使用并不意味着需要更少的内镜检查。
