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[一名接受同种异体移植治疗的21岁肾移植患者复发性人工瓣膜心内膜炎]

[Recurrent prosthetic endocarditis in a 21-year old patient with renal transplantation treated with allogeneic homograft].

作者信息

Sabol F, Jakubová M, Kolesár A, Stančák B, Beňa M, Podracký J, Podracká L, Cadník P, Spatenka J

机构信息

Klinika anestéziológie a intenzívnej mediciny VÚSCH, a.s., Kosice, Slovenská republika.

出版信息

Vnitr Lek. 2012 Jun;58(6):494-8.

Abstract

Prosthetic infective endocarditis is a possible complication of implantation of a prosthetic cardiac valve. Without early and effective treatment, it can have fatal consequences. One treatment option is use of an allogeneic cryopreserved homograft. This case report presents a 21-year old patient after kidney transplantation due to hereditary nephrotic syndrome and aortic valve replacement with aortic conduits. After fever was noted in the patient, prosthetic infective endocarditis was diagnosed by echocardiography and also confirmed by CT-3D examination. The cryopreserved aortic homograft was implanted at the Department of Cardiac Surgery. This along with additional conservative management effectively treated the infection. Based on literature data and our own experience, we believe that the treatment of prosthetic endocarditis after aortic valve replacement with cryopreserved homograft can be a method of choice.

摘要

人工心脏瓣膜感染性心内膜炎是人工心脏瓣膜植入术后可能出现的并发症。若不进行早期有效治疗,可能会导致致命后果。一种治疗选择是使用同种异体低温保存的同种移植物。本病例报告介绍了一名21岁因遗传性肾病综合征接受肾移植并使用主动脉管道进行主动脉瓣置换的患者。患者出现发热后,经超声心动图诊断为人工心脏瓣膜感染性心内膜炎,CT-3D检查也予以证实。低温保存的主动脉同种移植物在心脏外科植入。这与其他保守治疗措施一起有效治愈了感染。基于文献数据和我们自己的经验,我们认为用低温保存的同种移植物治疗主动脉瓣置换术后的人工瓣膜心内膜炎可以成为一种首选方法。

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