[小核糖核酸病毒感染的早期步骤]
[Early steps of picornavirus infection].
作者信息
Koike Satoshi
机构信息
Neurovirology Project, Tokyo Metropolitan Institute of Medical Science.
出版信息
Uirusu. 2011 Dec;61(2):183-91. doi: 10.2222/jsv.61.183.
PMID:22916565
Abstract
Picornaviridae is a large family of viruses that cause a variety of infectious diseases in humans and animals. It includes important viruses such as poliovirus, hepatisis A virus and foot and mouth disease virus. Early steps of infection play important roles in determining the host range and the target organs for each virus. Here, I review the recent advances in the studies of cellular receptors for picornaviruses, mechanisms of cell entry and viral uncoating.
摘要
小核糖核酸病毒科是一个庞大的病毒家族，可在人类和动物中引发多种传染病。它包括一些重要的病毒，如脊髓灰质炎病毒、甲型肝炎病毒和口蹄疫病毒。感染的早期步骤在决定每种病毒的宿主范围和靶器官方面起着重要作用。在此，我综述了小核糖核酸病毒细胞受体、细胞进入机制和病毒脱壳研究的最新进展。
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