Stuivenvolt Mischa, Mandl Ellen, Verheul Jeroen, Fleischeuer Ruth, Tijssen Cees C
Department of Neurology, St Elisabeth Hospital, Tilburg, The Netherlands.
BMJ Case Rep. 2012 Aug 24;2012:bcr0120125681. doi: 10.1136/bcr-01-2012-5681.
Choroid plexus papillomas (CPP) are rare tumours and spinal metastases of CPP are even less common. We report a 50-year-old woman with spinal drop metastases at Th9 and S1-2 6 years after total resection of a posterior fossa CPP. The metastasis at S1-2 was resected and histological examination showed transformation to an atypical CPP. Atypical transformation in a metastasis years after resection of a benign posterior fossa CPP has been described once. We would like to advocate craniospinal MRI at the time of initial diagnosis as well as periodic follow-up after total and subtotal resection of a posterior fossa CPP in adults at least once in 1 or 2 years, depending on the histological grading of the primary CPP. In our case report, this could have resulted in earlier diagnosis of the locoregional recurrence or of the spinal drop metastasis.
脉络丛乳头状瘤（CPP）是罕见肿瘤，而CPP的脊柱转移更为少见。我们报告一名50岁女性，在颅后窝CPP全切术后6年出现胸9和骶1 - 2水平的脊髓播散性转移。骶1 - 2处的转移灶被切除，组织学检查显示已转变为非典型CPP。良性颅后窝CPP切除数年之后转移灶发生非典型转变此前仅有过一次报道。我们建议在初始诊断时进行全脑脊髓MRI检查，对于成人颅后窝CPP全切或次全切术后，根据原发CPP的组织学分级，至少每1至2年进行一次定期随访。在我们的病例报告中，这样做本可更早诊断局部复发或脊髓播散性转移。
