大鼠脾脏中一种具有B血型决定簇的独特岩藻糖神经节苷脂。
A unique fucoganglioside with blood group B determinant in rat spleen.
作者信息
Nohara K, Suzuki M, Inagaki F, Ito H, Kaya K
机构信息
National Institute for Environmental Studies, Ibaraki.
出版信息
J Biochem. 1990 Oct;108(4):684-8. doi: 10.1093/oxfordjournals.jbchem.a123263.
A unique fucoganglioside was isolated from rat spleen and characterized by compositional analysis, methylation analysis, exoglycosidase treatment, negative ion fast atom bombardment (FAB) mass spectrometry, and proton NMR spectrometry. The ganglioside was identified as alpha Gal,Fuc-GM1(NeuGc), which has the blood group B determinant at the nonreducing termini, as shown below: (formula; see text) This is the first report describing the occurrence in nature of alpha Gal,Fuc-GM1 containing N-glycolylneuraminic acid.
从大鼠脾脏中分离出一种独特的岩藻糖神经节苷脂，并通过成分分析、甲基化分析、外切糖苷酶处理、负离子快原子轰击（FAB）质谱和质子核磁共振光谱对其进行了表征。该神经节苷脂被鉴定为αGal,Fuc-GM1(NeuGc)，其在非还原末端具有B血型决定簇，如下所示：（分子式；见正文）这是首次报道含有N-羟乙酰神经氨酸的αGal,Fuc-GM1在自然界中的存在情况。
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