Department of Cardiology, Ajou University School of Medicine, Suwon, Republic of Korea.
Catheter Cardiovasc Interv. 2013 Sep 1;82(3):370-6. doi: 10.1002/ccd.24634. Epub 2012 Dec 3.
We aimed to compare long-term clinical outcomes between modified mini-crush (modi-MC) technique with classic crush (crush) technique for treatment of bifurcation lesions.
The modi-MC technique showed excellent procedural success and favorable 9-month clinical outcomes.
From January 2005 to November 2009, we enrolled patients with de novo bifurcation lesions treated with modi-MC (n = 112 lesions in 111 patients) and crush technique (n = 69 lesions in 67 patients). Primary endpoint was rate of major adverse cardiac events (MACE), a composite of all-cause death, myocardial infarction (MI), and target lesion revascularization (TLR) at 3 years.
There was no significant difference in baseline characteristics. The modi-MC technique showed a significantly higher success rate of final kissing balloon inflation (84.1 vs. 98.2%, P = 0.001). After 3 years, MACE rate was significantly lower in the modi-MC group (25.4 vs. 12.6%, P = 0.030). The incidence of all-cause death was 7.5 vs. 2.7% (P = 0.087), MI was 4.5 vs. 1.8% (P = 0.290), TLR was 17.4 vs. 8.9% (P = 0.093) and stent thrombosis was 3.0 vs. 1.8% (P = 0.632) in the crush and modi-MC groups, respectively.
The modified mini-crush technique showed more favorable 3-year clinical outcomes compared to the classic crush technique.
比较改良微挤压（modi-MC）技术与经典挤压（crush）技术治疗分叉病变的长期临床结果。
modi-MC 技术显示出优异的手术成功率和良好的 9 个月临床结果。
2005 年 1 月至 2009 年 11 月，我们纳入了接受改良微挤压（modi-MC）技术（111 例患者 112 个病变）和挤压技术（crush 技术）（67 例患者 69 个病变）治疗的新发分叉病变患者。主要终点是 3 年时的主要不良心脏事件（MACE）发生率，即全因死亡、心肌梗死（MI）和靶病变血运重建（TLR）的复合终点。
两组患者的基线特征无显著差异。modi-MC 技术的最终对吻球囊扩张成功率明显更高（84.1% vs. 98.2%，P = 0.001）。3 年后，modi-MC 组的 MACE 发生率明显更低（25.4% vs. 12.6%，P = 0.030）。两组全因死亡率分别为 7.5% vs. 2.7%（P = 0.087）、MI 发生率分别为 4.5% vs. 1.8%（P = 0.290）、TLR 发生率分别为 17.4% vs. 8.9%（P = 0.093）和支架血栓形成发生率分别为 3.0% vs. 1.8%（P = 0.632）。
与经典挤压技术相比，改良微挤压技术显示出更有利的 3 年临床结果。
