Lashkeri Taher, Howell John M, Place Rick
Department of Emergency Medicine, Inova Fairfax Hospital for Children, Falls Church, VA, USA.
Pediatr Emerg Care. 2012 Sep;28(9):895-7. doi: 10.1097/PEC.0b013e318267c5b6.
Bronchiolitis is a dynamic condition, and predicting clinical deterioration can be difficult. The objective of this study was to determine whether capnometry readings among bronchiolitic children admitted to the hospital are significantly different from those discharged from the emergency department.
We prospectively studied a convenience sample of children younger than 24 months with clinical bronchiolitis. A single end-tidal CO2 (ETCO2) reading was taken before treatment, and a clinical work of breathing score was assigned to each patient. Treating physicians and nurses were blinded to capnometry readings. The decision to admit was based on the judgment of the attending physician. Descriptive statistics and appropriate hypothesis testing were performed. A receiver operating characteristic curve was constructed for the association between admission and capnometry readings. The α was set at 0.05 for all comparisons.
One hundred five children with bronchiolitis were included for study. Capnometry readings for admitted (mean, 32.6 mm Hg; 95% confidence interval [CI], 30.3-34.9 mm Hg) and discharged (mean 31.4 mm Hg; 95% CI 29.8-33.0 mm Hg) bronchiolitic children were not significantly different. Capnometry readings for low (mean, 31.7 mm Hg; 95% CI, 29.5-33.8 mm Hg), intermediate (mean, 32.1 mm Hg; 95% CI, 30.1-34.1 mm Hg), and high (mean, 30.5 mm Hg; 95% CI, 19.3-41.7 mm Hg) work of breathing (score) ranges were not significantly different.
Capnometry readings are not useful in predicting admission for children younger than 2 years with clinical bronchiolitis. There are no significant differences in capnometry readings among bronchiolitic children with low, medium, and high work of breathing scores.
细支气管炎是一种动态病症,预测临床病情恶化可能具有挑战性。本研究的目的是确定入住医院的细支气管炎患儿的二氧化碳测定读数与从急诊科出院的患儿的读数是否存在显著差异。
我们前瞻性地研究了一个方便样本,即年龄小于24个月且患有临床细支气管炎的儿童。在治疗前获取单次呼气末二氧化碳(ETCO2)读数,并为每位患者分配呼吸临床工作评分。治疗医生和护士对二氧化碳测定读数不知情。入院决定基于主治医生的判断。进行了描述性统计和适当的假设检验。构建了入院与二氧化碳测定读数之间关联的受试者工作特征曲线。所有比较的α设定为0.05。
纳入105名细支气管炎患儿进行研究。入住(平均值为32.6毫米汞柱;95%置信区间[CI]为30.3 - 34.9毫米汞柱)和出院(平均值为31.4毫米汞柱;95% CI为29.8 - 33.0毫米汞柱)的细支气管炎患儿的二氧化碳测定读数无显著差异。低(平均值为31.7毫米汞柱;95% CI为29.5 - 33.8毫米汞柱)、中(平均值为32.1毫米汞柱;95% CI为30.1 - 34.1毫米汞柱)、高(平均值为30.5毫米汞柱;95% CI为19.3 - 41.7毫米汞柱)呼吸工作(评分)范围的二氧化碳测定读数无显著差异。
二氧化碳测定读数对于预测2岁以下患有临床细支气管炎的儿童是否入院并无帮助。呼吸工作评分低、中、高的细支气管炎患儿的二氧化碳测定读数无显著差异。