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[三叉神经痛的病因与治疗]

[Etiology and therapy of trigeminal neuralgia].

作者信息

Soyka D

机构信息

Neurologische Universitäts-Klinik Kiel.

出版信息

Neurochirurgia (Stuttg). 1990 Oct;33 Suppl 1:11-3. doi: 10.1055/s-2008-1053587.

Abstract

Trigeminal neuralgia is an exactly defined syndrome with a non-uniform aetiology but an obviously uniform pathogenesis. A subdivision in an idiopathic and a symptomatic type is non-essential. In a part of the cases microvascular compression of the sensory root may be the cause of trigeminal neuralgia but there are some good arguments against this concept. Other causes such as multiple sclerosis, acoustic neuroma or carotid aneurysm are well known. The principle of neurosurgical procedures is either an interruption of the pain-conducting fibres or a non-specific manipulation at the Gasserian ganglion or the sensory root with the result of an interruption of abnormal ephapses and short-circuits which may recur later on. So microvascular decompression should not be considered to be a specific and causal therapeutic approach as well as the therapy of first choice for all cases.

摘要

三叉神经痛是一种定义明确的综合征,病因不统一,但发病机制明显一致。分为特发性和症状性类型并非必要。在部分病例中,感觉神经根的微血管压迫可能是三叉神经痛的病因,但也有一些有力论据反对这一概念。其他病因如多发性硬化、听神经瘤或颈动脉动脉瘤也广为人知。神经外科手术的原则要么是中断痛觉传导纤维,要么是在半月神经节或感觉神经根进行非特异性操作,结果是中断可能随后复发的异常突触传递和短路。因此,微血管减压不应被视为一种特异性的因果治疗方法,也不应被视为所有病例的首选治疗方法。

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