University of Medicine and Pharmacy & Cardiovascular Disease and Transplant Institute, Târgu Mureş, Romania.
Europace. 2012 Sep;14(9):1359-62. doi: 10.1093/europace/eus260.
The purpose of this EP Wire is to compare indications, techniques, implant strategy, and follow-up regarding cardiac resynchronization therapy (CRT) in several countries across Europe.
Forty-one centres, members of the EHRA-EP Research Network, responded to this survey and completed the questions. Thirty-two per cent of the responding centres always use CRT in heart failure (HF) patients with New York Heart Association functional class II and QRS width >120 ms, and 55% of the responding centres demand additional criteria when indicating CRT, most often QRS width >150 ms (49%) and echocardiographic criteria of asynchrony (34%). Only 10% of centres indicate CRT in all HF patients with QRS >120 ms and right bundle branch block, and 51% demand additional criteria, most frequently echocardiographic asynchrony parameters. The vast majority of centres also indicate CRT in patients with atrial fibrillation and standard criteria for CRT. In 24% of the centres, biventricular pacemaker (CRT-P) is implanted in all situations, unless there is an indication for secondary prevention of sudden cardiac death, while 10% always choose to implant a biventricular defibrillator (CRT-D). There are no clear evidence-based recommendations concerning the implant procedure and follow-up in patients treated with CRT; therefore, the chosen strategies vary widely from one centre to another.
This EP Wire survey shows a wide variation not only as far as CRT indications are concerned, but especially in techniques, implant strategy, and follow-up across the European countries.
本 EP 连线旨在比较欧洲多个国家心脏再同步治疗(CRT)的适应证、技术、植入策略和随访情况。
EHRA-EP 研究网络的 41 个中心对这项调查做出了回应并完成了相关问题。32%的应答中心在纽约心脏协会心功能分级 II 级和 QRS 宽度>120ms的心力衰竭(HF)患者中始终使用 CRT,55%的应答中心在指示 CRT 时需要额外的标准,最常见的是 QRS 宽度>150ms(49%)和超声心动图的不同步标准(34%)。只有 10%的中心在所有 QRS>120ms 并伴有右束支传导阻滞的 HF 患者中指示 CRT,51%需要额外的标准,最常见的是超声心动图不同步参数。绝大多数中心也在符合 CRT 标准的心房颤动和 HF 患者中指示 CRT。在 24%的中心中,除非有二级预防心脏性猝死的指征,否则在所有情况下都会植入双心室起搏器(CRT-P),而 10%的中心始终选择植入双心室除颤器(CRT-D)。在接受 CRT 治疗的患者中,植入程序和随访方面没有明确的循证推荐;因此,所选策略在各个中心之间差异很大。
本 EP 连线调查显示,不仅 CRT 的适应证存在广泛差异,而且在技术、植入策略和随访方面,欧洲各国之间也存在很大差异。