Suppr超能文献

游离组织移植在头颈部默克尔细胞癌中的作用。

The role of free tissue transfer in merkel cell carcinoma of the head and neck.

作者信息

Londino Iii Aldo V, Miles Brett A

机构信息

Department of Otolaryngology, The Mount Sinai Hospital, New York, NY 10029, USA.

出版信息

J Skin Cancer. 2012;2012:742303. doi: 10.1155/2012/742303. Epub 2012 Aug 15.

Abstract

Merkel cell carcinoma (MCC) is an uncommon neuroendocrine malignancy with a propensity for the head and neck. It typically presents asymptomatically in elderly Caucasians and is characterized by early local and regional spread. There is currently limited data on the appropriate algorithm for treatment of MCC. However, multimodal therapy with wide surgical excision with or without radiation therapy has become standard of care. The location of the primary tumor and intensive adjuvant therapy is often required, provides a challenge to the reconstructive head and neck surgeon. Occasionally, free tissue transfer reconstructive techniques are employed in the reconstruction of MCC defects. This paper will discuss the role of free tissue transfer as a reconstructive option after surgery for advanced head and neck MCC.

摘要

默克尔细胞癌(MCC)是一种罕见的神经内分泌恶性肿瘤,好发于头颈部。它通常在老年白种人中无症状出现,其特点是早期局部和区域扩散。目前关于MCC合适治疗方案的相关数据有限。然而,采用广泛手术切除并结合或不结合放射治疗的多模式治疗已成为标准治疗方法。原发肿瘤的位置以及通常需要的强化辅助治疗,给头颈重建外科医生带来了挑战。偶尔,在MCC缺损的重建中会采用游离组织移植重建技术。本文将探讨游离组织移植在晚期头颈部MCC手术后作为一种重建选择的作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a762/3426249/3be037df2c11/JSC2012-742303.001.jpg

相似文献

1
The role of free tissue transfer in merkel cell carcinoma of the head and neck.
J Skin Cancer. 2012;2012:742303. doi: 10.1155/2012/742303. Epub 2012 Aug 15.
2
Merkel cell carcinoma arising in the head and neck: optimizing therapy.
Am J Clin Oncol. 2001 Feb;24(1):35-42. doi: 10.1097/00000421-200102000-00006.
3
Merkel cell carcinoma: A series of seven cases.
Arch Plast Surg. 2019 Sep;46(5):441-448. doi: 10.5999/aps.2019.00465. Epub 2019 Sep 15.
4
Treatment of Merkel cell carcinoma of the head and neck: a systematic review.
Dermatol Surg. 2014 Dec;40(12):1273-83. doi: 10.1097/DSS.0000000000000131.
6
Merkel cell carcinoma of the head and neck: pathogenesis, current and emerging treatment options.
Onco Targets Ther. 2015 Aug 19;8:2157-67. doi: 10.2147/OTT.S72202. eCollection 2015.
7
Merkel cell carcinoma of the head and neck.
Oral Oncol. 2004 Sep;40(8):773-9. doi: 10.1016/j.oraloncology.2003.11.005.
9
Recent Therapeutic Advances and Change in Treatment Paradigm of Patients with Merkel Cell Carcinoma.
Oncologist. 2019 Oct;24(10):1375-1383. doi: 10.1634/theoncologist.2018-0718. Epub 2019 Apr 8.

引用本文的文献

2
Multimodal Strategy in Localized Merkel Cell Carcinoma: Where Are We and Where Are We Heading?
Int J Mol Sci. 2021 Sep 30;22(19):10629. doi: 10.3390/ijms221910629.
3
Merkel cell carcinoma: an illustrative case and review.
Postepy Dermatol Alergol. 2014 Oct;31(5):325-8. doi: 10.5114/pdia.2014.40797. Epub 2014 Oct 22.
4
Emerging and mechanism-based therapies for recurrent or metastatic Merkel cell carcinoma.
Curr Treat Options Oncol. 2013 Jun;14(2):249-63. doi: 10.1007/s11864-013-0225-9.

本文引用的文献

3
Microsurgical reconstruction of large, locally advanced cutaneous malignancy of the head and neck.
Int J Surg Oncol. 2011;2011:415219. doi: 10.1155/2011/415219. Epub 2011 Oct 20.
4
Deep inferior epigastric artery perforated rectus abdominis free flap for head and neck reconstruction.
Eur Arch Otorhinolaryngol. 2012 Apr;269(4):1219-24. doi: 10.1007/s00405-011-1749-x. Epub 2011 Aug 25.
5
Merkel cell polyomavirus status is not associated with clinical course of Merkel cell carcinoma.
J Invest Dermatol. 2011 Aug;131(8):1631-8. doi: 10.1038/jid.2011.115. Epub 2011 May 12.
6
Microvascular free tissue transfer in the reconstruction of scalp and lateral temporal bone defects.
J Craniofac Surg. 2011 May;22(3):801-4. doi: 10.1097/SCS.0b013e31820f3730.
7
The role of radiotherapy alone in patients with merkel cell carcinoma: reporting the Australian experience of 43 patients.
Int J Radiat Oncol Biol Phys. 2010 Nov 1;78(3):703-9. doi: 10.1016/j.ijrobp.2009.08.011. Epub 2009 Nov 24.
8
Routine omission of sentinel lymph node biopsy for merkel cell carcinoma <= 1 cm is not justified.
J Clin Oncol. 2010 Jan 1;28(1):e7. doi: 10.1200/JCO.2009.25.9937. Epub 2009 Nov 23.
9
Single-institution series of early-stage Merkel cell carcinoma: long-term outcomes in 95 patients managed with surgery alone.
Ann Surg Oncol. 2009 Nov;16(11):2985-93. doi: 10.1245/s10434-009-0615-1. Epub 2009 Jul 16.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验