Jochimsen E, Sikkink J, Marx J J
Eau Claire Family Medicine Clinic, WI 54701.
Wis Med J. 1990 Dec;89(12):677-81.
We conducted a seroprevalence survey of antibodies to Borrelia burgdorferi in West Central Wisconsin, an area endemic for Lyme disease. One hundred and thirty-seven of 153 patients having blood drawn at the Eau Claire Family Medicine Clinic and the associated rural Augusta practice participated in the study and were tested for the presence of antibodies to B burgdorferi and questioned about Lyme disease risk factors. An enzyme-linked immunosorbent assay showed that 15 (10.9%) of the 137 persons had serological evidence of exposure to B burgdorferi. None of these 15 persons reported a past or current history of clinical Lyme disease, and they were not found to have more symptoms commonly associated with Lyme disease than seronegative patients. We conclude that the prevalence of positive Lyme serologies in this area is similar to that of other endemic areas and that subclinical or asymptomatic infection probably accounts for many of these positive results.
我们在威斯康星州中西部开展了一项针对伯氏疏螺旋体抗体的血清流行率调查，该地区为莱姆病的地方性流行区。在欧克莱尔家庭医学诊所及相关的奥古斯塔乡村医疗机构进行采血的153名患者中，有137名参与了研究，并接受了伯氏疏螺旋体抗体检测，同时被询问了莱姆病风险因素。酶联免疫吸附测定显示，137人中有15人（10.9%）有接触伯氏疏螺旋体的血清学证据。这15人中没有人报告过去或现在有临床莱姆病病史，而且与血清学阴性的患者相比，他们并未被发现有更多与莱姆病相关的常见症状。我们得出结论，该地区莱姆病血清学阳性率与其他地方性流行区相似，许多阳性结果可能是由亚临床或无症状感染导致的。
