Department of Surgery, FM/UFMG.
Braz J Otorhinolaryngol. 2012 Jul-Aug;78(4):103-7. doi: 10.1590/S1808-86942012000400019.
Salvage laryngectomy in patients treated with organ preservation protocols is associated with high rates of postoperative complications. The use of non-irradiated tissue flaps in pharyngeal reconstruction could reduce the incidence of these complications.
This study aims to evaluate the usefulness of the pectoralis major myocutaneous flap in preventing salivary fistulae during the postoperative period of salvage total laryngectomy (TL).
This retrospective study enrolled 31 patients operated between April of 2006 and May of 2011. All patients had advanced cancer at the time of the salvage procedure and had been treated with chemoradiotherapy or radiotherapy alone. Pharyngeal reconstruction was performed using pectoralis major myocutaneous flap in 19 cases (61%); primary wound closure occurred in 12 patients (39%).
Salivary fistulae occurred in 16% of the patients who received the flap and in 58% of the patients with primary closure of the pharynx (p < 0.02). No statistically significant differences were noted between the groups with respect to the mean time for fistula formation, reintroduction of an oral diet, or use of a nasoenteric tube for feeding.
The pectoralis major myocutaneous flap was found to reduce the incidence of salivary fistulae in salvage laryngectomy procedures.
目的:本研究旨在评估胸大肌肌皮瓣在预防挽救性全喉切除术后唾液瘘中的作用。
材料与方法:本回顾性研究纳入了 2006 年 4 月至 2011 年 5 月期间接受手术的 31 例患者。所有患者在挽救性手术时均患有晚期癌症,并接受过放化疗或单纯放疗。19 例(61%)患者行胸大肌肌皮瓣咽成形术,12 例(39%)患者行一期咽闭合术。
结果:接受皮瓣的患者中有 16%发生唾液瘘,而行一期咽闭合术的患者中有 58%发生唾液瘘(p<0.02)。两组患者在瘘管形成时间、重新开始口服饮食以及使用鼻肠管喂养方面无统计学差异。
结论:胸大肌肌皮瓣可降低挽救性喉切除术唾液瘘的发生率。